Sort   by:  
 Page size 
ProteomicsProtein networks associated with native metabotropic glutamate 1 receptors (mGlu1) in the mouse cerebellum.
To identify novel mGlu1-associated protein complexes in the mouse cerebellum, we used an unbiased tissue-specific proteomic approach, namely co-immunoprecipitation followed by liquid chromatography/tandem mass spectrometry analysis.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD040886 | Pride
Glutamate receptors  cerebellum  kctd12  immunoprecipitation  proteomics 
ProteomicsThe Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi
We quantified the proteome of Dsc complex mutants (tul1gld1) and ESCRT mutants (vps4). Therefore we used stable isotope labeling with amino acids in cell culture (SILAC) to identify changes in the membrane proteome of tul1gld1orvps4 cells relative to WT cells or gld1 cells (labeled with “heavy” [13C...
ORGANISM(S): Candida albicans (Yeast) 
2025-05-07 | PXD055553 | Pride
Degron Dsc complex Quality control Escrt Golgi Lipids Ubiquitin 
ProteomicsTXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
Entry and exit from cellular quiescence require dynamic adjustments in nutrient acquisition, yet the mechanisms by which quiescent cells downregulate amino acid (AA) transport remain poorly understood. Here we show that cells entering quiescence selectively target plasma membrane-resident AA transpo...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD066527 | Pride
Nutrient transporter Hect-type ubiquitin ligase Ppxy Quiescence Arrestin Endocytosis 
ProteomicsFecal detection of calprotectin subunits links IBD activity with chronicity of intestinal inflammation.
Quantification of the human S100A8/S100A9 tetrameric protein complex in stool, referred to as fecal calprotectin, is an extensively validated biomarker supporting the diagnosis and management of gastrointestinal diseases1,2. The quaternary protein structures (called configuration here) of S100A8 and...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD068250 | Pride
Calprotectin  s100a8  s100a9  inflammatory bowel diseases  gut  crohn's disease  ulcerative colitis  adaptive immunity  inflammation  biomarker  nlrp1  inflammasome 
UnknownLAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
Not available
S-JCBD-201703061 | bioimages
Sort   by:  
 Page size