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MetabolomicsMultiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level (Metabolite profiling)

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9830 | MetaboLights
UnknownOverexpression of cyclin F/CCNF as an independent prognostic factor for poor survival in clear cell renal cell carcinoma.
Not available
S-EPMC11039610 | biostudies-literature
ProteomicsLinking acetyl-CoA labelling and histone acetylation dynamics for accurate determination of acetylation rates via ordinary differential equations
To study complex biological systems, multi-omics methods have become an important tool. They integrate data from multiple biological layers, such as the metabolome and the proteome, to gain better insights of the processes happening. However, challenges remain both in sample preparation for measurem...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051487 | Pride
Human Lc-msms Acetylcoa Ptm Histone Acetylation Hek93t 
UnknownMetastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a.
Not available
S-EPMC5974340 | biostudies-literature
UnknownConserved structural and functional aspects of the tripartite motif gene family point towards therapeutic applications in multiple diseases.
Not available
S-EPMC5721676 | biostudies-literature
UnknownBinding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants.
Not available
S-EPMC4933183 | biostudies-literature
UnknownRapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli.
Not available
S-EPMC4087019 | biostudies-literature
ProteomicsTowards a better understanding the testicular proteome of domestic pig
For gaining additional insights into the composition of the testicular proteome of the domestic pig (Sus scrofa domestica), we conducted 2DE-MS. Two-dimensional SDS PAGE was run on testicular lysates of three boars, with three gels per boar. Upon matching across gels, we arbitrarily selected protein...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-08-12 | PXD015649 | Pride
Proteomics Sus srofa 2de-ms 
UnknownMechanical stability of αT-catenin and its activation by force for vinculin binding.
Not available
S-EPMC6727763 | biostudies-literature
UnknownThe C2 domains of dysferlin: roles in membrane localization, Ca2+ signalling and sarcolemmal repair.
Not available
S-EPMC9285653 | biostudies-literature
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