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MetabolomicsCeramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma
Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...
2023-12-20 | MTBLS7649 | MetaboLights
TranscriptomicsTranscriptome profiling of H. polymorpha in response to hydrogen peroxide exposure
To gain insight into the basic mechanism of Hydrogen peroxide detoxification in the methylotrophic yeast, H. polymorpha, we analyzed changes in transcriptional profiles in response to hydrogen peroxide exposure. Total RNA samples were collected from H. polymorpha cells after 30 min incubation with 0...
ORGANISM(S): Ogataea angusta 
2015-02-28 | E-GEOD-43048 | biostudies-arrayexpress
UnknownFerritin Level Is Positively Associated with Chronic Kidney Disease in Korean Men, Based on the 2010-2012 Korean National Health and Nutrition Examination Survey.
Not available
S-EPMC5129268 | biostudies-literature
ProteomicsIntegrative multi-scale physiological, metabolic, and proteomic reprogramming in tomato under polyethylene microplastic stress
This dataset contains bottom-up, label-free proteomic data from tomato roots exposed to polyethylene microplastics under soil conditions. Tomato plants (Solanum lycopersicum cv. Super Dotaerang) were grown for 48 days in agricultural soil containing 0%, 1%, or 5% (w/w) polyethylene microplastics. Ro...
ORGANISM(S): root Solanum lycopersicum 
2026-10-20 | PXD076181 | Pride
Tomato  solanum lycopersicum  root proteomics  polyethylene microplastics  label-free quantification  abiotic stress  dda  bottom-up proteomics 
ProteomicsAnalysing the Mechanism of Mitochondrial Oxidation-induced Cell Death Using a Multifunctional Iridium(III) Photosensitiser
Mitochondrial oxidation-induced cell death, a physiological process triggered by various cancer therapeutics to induce oxidative stress on tumours, has been challenging to investigate owing to the difficulties in generating mitochondria-specific oxidative stress and monitoring mitochondrial response...
ORGANISM(S): Homo sapiens (Human) 
2021-03-23 | PXD022163 | Pride
Photosensitiser Iridium(iii) complex Mitochondrial oxidation-induced cell death Photo-crosslinking Depolarisation 
TranscriptomicsTranscriptome profiling of Hansenula polymorpha in response to sulfur starvation and cadmium stress
Transcriptome profiling analysis of the Hansenula polymorpha MET4 gene deletion strain have been carried out to obtain comprehensive information on the HpMet4p-mediated regulatory networks in association with the cadmium (Cd) detoxification and sulfur regulation in H. polymorpha. Total RNA samples w...
ORGANISM(S): Ogataea angusta 
2014-07-31 | E-GEOD-31197 | biostudies-arrayexpress
ProteomicsAn in situ ascorbate peroxidase 2-based labeling method and its application in detecting exosome proteins released from mouse proximal tubule cells under oxidative stress
Here, we developed an in situ labeling approach to identify exosome-loaded proteins, which bypasses the traditional exosome isolation steps. In this method, an engineered ascorbate peroxidase targeting to endosomes-destined exosomes was used to label proteins loaded inside exosomes released from kid...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD025852 | Pride
Apex2 Kidney Mouse Oxidative stress Exosomes Lc-ms/ms 
GenomicsChIP-seq analysis of LPS trained BMDMs reveals remodeling of Histone 3 Lysine 4 tri-methylation (H3K4me3)
The aim of this study is to profile the distribution of the active histone modification H3K4me3 in BMDMs from WT and SLC1A5_var transgenic mice after low-dose LPS training. We compared the data of ChIP-seq performed on fragmented chromatin immunoprecipitated with anti-H3K4me3 antibody in naive and t...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16196 | biostudies-arrayexpress
TranscriptomicsHigh succinic acid tolerance E.coli (DST160)
To understand cell responses against high succinate stress, a continuous culture was performed for 9 months using a wild Escherichia coli under gradually increasing succinate stress. The final adapted strain against high succinate stress, named DST160, was able to grow with no lag phase in medium co...
ORGANISM(S): Escherichia coli str. K-12 substr. W3110 
2009-10-29 | E-GEOD-17991 | biostudies-arrayexpress
TranscriptomicsEffect pck or ppc expression on intracellular ATP
Up-regulation of motility genes and biosynthesis genes were found in the pck expressing high ATP cell by transcriptome analysis while catabolism genes were down-regulated. Keywords: response depends on intracellular ATP concentration derived by pck or ppc overexpression 1. pck or ppc overexpressing ...
ORGANISM(S): Escherichia coli 
2010-06-09 | E-GEOD-8532 | biostudies-arrayexpress
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