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ProteomicsThe natural diversity of the yeast proteome links aneuploidy tolerance to genome-wide proteome
Recent advancements in genome sequencing have facilitated accessing the natural genetic diversity of species, unveiling hidden genetic traits, clarifying gene functions, and the degree to which laboratory studies can be generalized. One notable discovery is the frequent (~20%) aneuploidy - an imbala...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-03-11 | PXD044526 | Pride
Large-scale Proteomics Lab-engineered strains Yeast Diversity Wild isolates High-throughput Aneuploidy 
ProteomicsEngineered yeast strains expressing human glycolytic enzymes
Ewout Knibbe et al.,(Pascale Daran-Lapujade Lab, TU Delft) report on engineered yeast strains to express the human glycolysis pathway instead of the native pathway enzymes. The goal of the project is to investigate the conservation of these functions between species. The engineered yeast strains wer...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-12-22 | PXD025349 | Pride
Qe plus Yeast Tmt experiment Glycolysis 
ProteomicsLacticaseibacillus paracasei derived Extracellular vesicles LC-MS/MS
Owing to their ability to secrete antimicrobials and benefit human health, lactic acid bacteria (LAB) cultures are an attractive nontoxic alternative to antibiotics for preserving food and combating pathogenic infections. Given that this strategy has several limitations, including strain-dependent a...
ORGANISM(S): Lactobacillus paracasei ATCC 334 
2025-07-21 | PXD059432 | Pride
Surface-displayed protein Lacticaseibacillus paracasei derived extracellular vesicles Lc-ms/ms 
UnknownShared and Independent Genetic Basis of Resistance to Bt Toxin Cry2Ab in Two Strains of Pink Bollworm.
Not available
S-EPMC7224296 | biostudies-literature
UnknownResourceful and economical designing of fermentation medium for lab and commercial strains of yeast from alternative feedstock: 'transgenic oilcane'.
Not available
S-EPMC11786580 | biostudies-literature
ProteomicsThe natural diversity of the yeast proteome links aneuploidy tolerance to protein turnover
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions, and allows assessment of the generalizability of laboratory findings. One notable discovery made in Saccharomyces cerevisiae natural isolates is frequent (~20%) aneuploidy – an imbalance in ch...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-03-13 | PXD048219 | Pride
Aneuploidy Protein stability Yeast Silac 
ProteomicsEngineering stringent genetic biocontainment of yeast with a protein stability switch
Synthetic biology holds immense promise to tackle key problems we are facing, for instance in resource use, environmental health, and human health care. However, comprehensive safety measures are needed to deploy genetically engineered microorganisms in open-environment applications. Intrinsic, gene...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-02-05 | PXD042326 | Pride
Genomic safeguards Biocontainment Biosafety High-throughput genome engineering 
TranscriptomicsRestoration and reinforcement of acclimatizing responses during the adaptation of an unfit, metabolically engineered strain
Organisms cope with physiological stressors through acclimatizing mechanisms in the short-term, and through adaptive mechanisms over evolutionary timescales. Whereas the former offer a consistent and largely predictable buffer against stressors, myriad paths of adaptation are often possible. Our wor...
ORGANISM(S): Methylobacterium extorquens AM1 
2012-11-08 | E-GEOD-42116 | biostudies-arrayexpress
UnknownDevelopment and Characterization of an Antimicrobial Polydopamine Coating for Conservation of Humpback Whales.
Not available
S-EPMC6759777 | biostudies-literature
UnknownThe Translational Coupling of Daidzein Reductase and Dihydrodaidzein Racemase Genes Improves the Production of Equol and Its Analogous Derivatives in Engineered Lactic Acid Bacteria.
Not available
S-EPMC12645574 | biostudies-literature
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