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ProteomicsLactonase Specificity is Key to Quorum Quenching in Pseudomonas aeruginosa
The human opportunistic pathogen Pseudomonas aeruginosa orchestrates the expression of many genes in a cell density-dependent manner by using a molecular communication system referred to as quorum sensing (QS). This bacterium uses an intricate network of regulators and QS molecules known as autoindu...
ORGANISM(S): Escherichia coli 
2020-05-27 | PXD017421 | Pride
Quorum sensing (qs) Lc-msms Virulence Ahl (n-acyl-homoserine lactone) Lactonase Quorum quenching (qq) Pseudomonas aeruginosa 
ProteomicsProteome analysis of Pectobacterium atrosepticum cells and inhibition effect of exogeneous treatment with lactonase.
The proteome of Pectobacterium atrosepticum cells was established by shotgun proteomics and compared to the proteome of the same bacterium treated with exogeneous lactonase to characterize the molecular modifications induced by the treatment with a quorum sensing inhibitor.
ORGANISM(S): Pectobacterium atrosepticum 
2025-03-25 | PXD054011 | Pride
Phytopathogen Metabolism Virulence Proteomics Pectobacterium Lactonase Soft rot Bacteria Quenching Quorum sensing 
GenomicsMaize root bacteria degrade host-specialized metabolites through the lactonase BxdA
Maize root bacteria degrade host-specialized metabolites through the lactonase BxdA
PRJNA1096617 | ENA
Genomics
Lactonase impact on synthetic community structure
PRJNA1190957 | ENA
UnknownSacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase.
Not available
S-EPMC4068969 | biostudies-literature
UnknownAhlX, an N-acylhomoserine Lactonase with Unique Properties.
Not available
S-EPMC6669651 | biostudies-literature
UnknownQuorum quenching by endophytic Bacillus cereus AL1: a lactonase-based anti-virulence strategy against Pseudomonas aeruginosa.
Not available
S-EPMC12539043 | biostudies-literature
UnknownDifferential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.
Not available
S-EPMC3781021 | biostudies-literature
TranscriptomicsMaize root bacteria degrade host-specialized metabolites through the lactonase BxdA
Root exudates contain specialised metabolites that affect the plant’s root microbiome. How host-specific microbes cope with these bioactive compounds, and how this ability shapes root microbiomes, remains largely unknown. We investigated how maize root bacteria metabolise benzoxazinoids, the main sp...
ORGANISM(S): Microbacterium sp. LMB2-1.2 
2024-04-05 | GSE263275 | GEO
UnknownMomL, a novel marine-derived N-acyl homoserine lactonase from Muricauda olearia.
Not available
S-EPMC4277582 | biostudies-literature
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