Sort   by:  
 Page size 
Transcriptomicsshort and long attack latency mice
Two wild house mice lines were genetically selected for short and long attack latency. Mice with an attack latency <50s or >600s were considered short attack latency mice (SAL) and long attack latency mice(LAL) respectively. RNA from the hippocampus of 14 SAL or 14 LAL mice was pooled and used as in...
ORGANISM(S): Mus musculus 
2003-10-30 | E-GEOD-786 | biostudies-arrayexpress
GenomicsCapsicum annuum cultivar:annum Punjab lal
Capsicum annuum cultivar:annum Punjab lal Transcriptome or Gene expression
PRJNA321972 | ENA
ProteomicsFrom LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver pathology worldwide, closely associated with obesity and metabolic disorders. Increasing evidence suggests that macrophages play a crucial role in the development of MASLD. Several human studies have shown an inver...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-01 | PXD056343 | Pride
Mouse Timstof pro 2 
ProteomicsRegional differences in the small intestinal proteome of control mice and of mice lacking lysosomal acid lipase
Background: Despite recent studies investigating the involvement of single cells in regional differences of the small intestine (SI), the metabolic contribution of the duodenum, jejunum, and ileum to the overall intestinal metabolism is still unclear. Basic procedures and main findings: Using an unt...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-20 | PXD048378 | Pride
Metabolism Proteomics Lal Small intestine Macrophages 
UnknownFrom LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism.
Not available
S-EPMC7618626 | biostudies-literature
TranscriptomicsCustom-designed lipid-based nanoparticles efficiently deliver mRNA to reverse the pathogenesis of LAL deficiency in a preclinical model
Lysosomal acid lipase (LAL) is a crucial enzyme responsible for the hydrolysis of triglycerides (TGs) and cholesteryl esters (CEs) in the lysosomes. LAL deficiency results in the extensive storage of CEs and TGs in the liver and the spleen, inducing hepatosplenomegaly, and can be a life-threatening ...
ORGANISM(S): Mus musculus 
2024-12-06 | GSE280933 | GEO
TranscriptomicsTranscription profiling of Streptomyces coelicolor wild type and delta0877 and delta7173 mutant strains
Gene expression analysis of S. coelicolor M145 wild type strain, and mutants delta0877 and delta 7173. RNA samples were extracted from 48 h culture samples during growth in flasks in defined mineral medium MG supplemented with 5% of yeast extract. Cy5 labelled genomic DNA was used as the common ref...
ORGANISM(S): Streptomyces coelicolor 
2009-04-17 | E-MEXP-2132 | biostudies-arrayexpress
GenomicsCustom-designed lipid-based nanoparticles efficiently deliver mRNA to reverse the pathogenesis of LAL deficiency in a preclinical model
Custom-designed lipid-based nanoparticles efficiently deliver mRNA to reverse the pathogenesis of LAL deficiency in a preclinical model
PRJNA1181265 | ENA
ProteomicsComparative gene expression profiling of mutants of Amycolatopsis mediterranei S699
The project aims to unveil the mechanism of rifamycin and its analog production by wild type A. mediterranei S699 and mutant A. mediterranei DCO#34 known to produce 24-desmethylrifamycin B at two time points. Stain that donot produce this molecule is taken as the negative control in the study.
ORGANISM(S): Amycolatopsis mediterranei S699 
2021-03-11 | PXD016416 | Pride
24-desmethylrifamycin b Amycolatopsis 42h and 96h Production mechanism Rifamycin 
UnknownImpact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration.
Not available
S-EPMC10209539 | biostudies-literature
Sort   by:  
 Page size