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MetabolomicsClovamide, a hydroxycinnamic acid amide, is a resistance factor against Phytophthora spp. in Theobroma cacao
The hydroxycinnamic acid amides (HCAAs) are a diverse group of plant specialized phenylpropanoid metabolites distributed widely in the plant kingdom and are known to be involved in tolerance to abiotic and biotic stress. The HCAA clovamide is reported in a small number of distantly related species. ...
2020-12-17 | MTBLS2154 | MetaboLights
ProteomicsInternal Ribosome Entry Site RNAs act in trans through an antisense sequence
SINEUPs are antisense long non-coding RNAs (lncRNAs) that increase translation of overlapping mRNAs through the activity of two domains: an embedded SINEB2 sequence UP-regulates translation (Effector Domain) while the antisense region provides target specificity (Binding Domain). In this study, we ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD028571 | Pride
Proteomics Circ5533 Pxk Binding domain Sineups 
ProteomicsInteractome Analysis of NDP52 by LC-MS/MS
NDP52 is an autophagy receptor, with known cytoplasmic binding partners. However, little is known regarding the nuclear functions of this protein. To investigate possible nuclear roles of NDP52 and find new interacting proteins, we performed LC-MS/MS affinity purification experiments.
ORGANISM(S): Homo sapiens (Human) 
2023-03-29 | PXD030238 | Pride
Alpha-amanitin Lc-ms/ms Ndp52 Hela 
ProteomicsEnhancement of Tryptic Peptide Signals from Tissue Sections using MALDI IMS Post-ionization (MALDI-2)
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for highly multiplexed, unlabeled mapping of analytes from tissue sections. However, further work is needed to improve sensitivity and depth of coverage for protein and peptide IMS. Laser-based post-ionization ...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD023877 | Pride
Kidney Imaging mass spectrometry Maldi-2 Lc-ms/ms 
ProteomicsTools for flesh quality and shelf life monitoring of high pressure processed European sea bass (Dicentrarchus labrax) fillets
Fresh fish are highly perishable food products and their short shelf-life limits their commercial exploitation, leads to waste and has a negative impact on aquaculture sustainability. New non-thermal food processing methods, such as High pressure (HP), are being investigated to prolong shelf-life wh...
ORGANISM(S): Dicentrarchus labrax 
2019-11-06 | PXD012737 | Pride
European sea bass  fillet  high pressure  metagenomics  proteomics  swath 
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
MetabolomicsExploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation.

SCOPE: Cow's milk allergy (CMA) is one of the most prevalent food allergies in early childhood, often treated via elimination diets including standard amino acid-based formula or amino acid-based formula supplemented with synbiotics (AAF or AAF-S). This work aimed to assess ...

2024-09-02 | MTBLS8954 | MetaboLights
TranscriptomicsGene Expression Data Following Chronic Vehicle or Fluoxetine Treatment in Thirty Mouse Inbred Lines
In order to understand how biochemical and genetic differences correlate with treatment response, we measured depressive-like behavior, gene expression and the levels of thirty-six neurobiochemical analytes across a panel of genetically-diverse mouse inbred lines after chronic treatment with vehicle...
ORGANISM(S): Mus musculus 
2011-08-30 | E-GEOD-28644 | biostudies-arrayexpress
ProteomicsIdentification of O-GlcNAcylated proteins and mapping of O-GlcNAc sites using Click Chemistry following extensive fractionation of extracted proteins
The O-N-acetyl-β-D-glucosaminylation, termed O-GlcNAcylation, is an atypical glycosylation corresponding to the transfer of a unique saccharide, the N-acetyl-β-D-glucosamine, on the hydroxyl group of serine and threonine amino acids of nuclear, cytosolic and mitochondrial proteins. Because of its dy...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-21 | PXD004860 | Pride
Muscle Mouse O-glcnacylation Lc_msms Sites mapping Post-translational modifications C2c12 muscle cells 
TranscriptomicsTamoxifen-resistant human breast cancer cell lines
A functional genetic screen to identify genes causing tamoxifen resistance in an estrogen-dependent human breast cancer cell model was performed. By insertion of defective retrovirus into the genome, individual genetic changes were introduced at random in ZR-75-1 cells. Subsequently, infected cells ...
ORGANISM(S): Homo sapiens 
2009-12-09 | E-GEOD-14513 | biostudies-arrayexpress
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