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TranscriptomicsSingle cell RNA on hemocytes from wandering larvae of Drosophila melanogaster not infested and infested by Leptopilina boulardi
We aimed at characterizing the diverse hemocyte populations present in the hemolymph of the Drosophila larvae. The hemocytes were collected from wandering larvae infested by wasp (WI) or not infested (NI). The hemocytes were then sequenced using 10x genomics technology.
ORGANISM(S): Drosophila melanogaster 
2020-03-12 | E-MTAB-8698 | biostudies-arrayexpress
TranscriptomicssmallRNA-seq of Solanum lycopersicum bearing the sulfurea epiallele in nrpe1 versus WT
Plants bearing a sulfurea epiallele (TAB2sulf) were crossed with nrpe1 (largest polV subunit) mutants in Solanum Lycopersicum. 7 plants of a F3 progeny expected to be 100% TAB2sulf and segregating for the nrpe1 mutation were sequenced. 4 plants bear the nrpe1 mutation and 3 plants have NRPE1 WT all...
ORGANISM(S): Solanum lycopersicum 
2021-07-02 | E-MTAB-10565 | biostudies-arrayexpress
TranscriptomicsComprehensive identification of long non-coding RNAs expressed during zebrafish embryogenesis [RNA_seq]
Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that structurally resemble mRNAs but do not encode proteins. Recent genome-wide studies in human and mouse have annotated lncRNAs expressed in cell lines and adult tissues, but a systematic analysis of lncRNAs expressed during ve...
ORGANISM(S): Danio rerio 
2011-11-17 | E-GEOD-32898 | biostudies-arrayexpress
TranscriptomicsZEB1 in 3T3-L1 differentiation (RNA-seq)
We aimed to characterise genome-wide gene expression changes upon ZEB1 knockdown in 3T3-L1 cells at distinct timepoints of adipogenic differentiation (days 0 and 2), performing replicate experiments.
ORGANISM(S): Mus musculus 
2014-09-17 | E-MTAB-2538 | biostudies-arrayexpress
TranscriptomicsInvestigating the mechansisms associated with Folfiri-induced muscle wasting in normal mice
Purpose of the study: the goal of this study was to use Next-generation sequencing to investigate the gene expression profile of skeletal muscle from mice exposed to chemotherapy (Folfiri) for up to 5 weeks. Methods: Standard methods were used for polyA mRNA-seq library construction, EZBead preparat...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-80473 | biostudies-arrayexpress
ProteomicsDownregulation of RING ligase praja2 boosts receptor tyrosine kinases in kidney cancer
Clear cell renal cell carcinoma (ccRCC) is the most common variant of kidney cancer in the adult population. Late diagnosis, resistance to therapeutics and recurrence of metastatic lesions account for the highest mortality rate among kidney cancer patients. Identifying novel biomarkers for early can...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD034966 | Pride
Lc-ms-ms Praja2 Interactome 
ProteomicsThe role of FKBP51 in the activation of Akt oncogenic pathway
FKBP51 is an immunophilin with a relevant role in sustaining cancer cell growth and aggressiveness, particularly in melanoma. Thanks to its scaffold and isomerase activities, mediated by its TPR and FK1 domains, respectively, FKBP51 participates in several signaling pathways. Akt is a serine-threoni...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033828 | Pride
Lc-ms-ms Fkbp51 Interactome 
ProteomicsLIN28a modulates ESC differentiation by interacting with PRC2
LIN28a is an RNA binding protein that was initially characterized for its role in the negative regulation of let-7 microRNA biogenesis. In the last years a new role in the regulation of mRNA translation has been highlighted. This mechanism seems to be particularly relevant in the exit of embryonic s...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-05 | PXD049332 | Pride
Lin28a Interactome Embryonic stem cells Rna binding protein 
ProteomicsThylakoid protein phosphorylation in Physcomitrella patens
Physcomitrella patens is a model plant representing the group of mosses, which diverged from vascular plant ancestors early after land colonization. To investigate the unique characteristic of the composition and post-translational regulation of Physcomitrella patens photosynthetic apparatus, we hav...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2019-05-08 | PXD012501 | Pride
Physcomitrella patens  moss  thylakoids  photosynthesis  photosystem ii  stn8 kinase  protein phosphorylation  n-terminal acetylation  nlc-msms 
TranscriptomicsGene expression profiling during human neuronal differentiation
Transcriptome analysis of human neuroepithelial stem (NES) cells during differentiation
ORGANISM(S): Homo sapiens 
2019-08-31 | E-MTAB-7128 | biostudies-arrayexpress
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