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we performed large-scale co-immunoprecipitation (co-IP) using a DOT1L antibody with nuclear extract from K562 cells, and characterized immunoprecipitated proteins by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2021-06-18 | PXD024874 | Pride
Affinity purification coupled to mass spectrometry is often used as a complementary technique to BioID experiments, and the data presented here complements another project. To infer processes involving Ku70, we used AP-MS to identify candidate proteins that may interact with Ku70 and compared these ...
ORGANISM(S): Homo sapiens (Human) 
2019-01-03 | PXD010930 | Pride
Solute carrier (SLC) transporters form a major superfamily which transport a wide range of substrates across cellular and organellar membranes. The superfamily consists of about 450 members and includes passive transporters, antiporters and symporters. To ensure the homeostatic regulation of metabol...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD055605 | Pride
Alternative polyadenylation (APA) is a widespread mechanism of gene regulation that generates transcript isoforms with distinct 3' ends. While several RNA-binding proteins (RBPs) are known to regulate APA, the roles of the vast majority of RBPs in this process remain poorly characterized. Using a la...
ORGANISM(S): Homo sapiens 
2026-06-29 | GSE290248 | GEO
Alternative polyadenylation (APA) is a widespread mechanism of gene regulation that generates transcript isoforms with distinct 3' ends. While several RNA-binding proteins (RBPs) are known to regulate APA, the roles of the vast majority of RBPs in this process remain poorly characterized. Using a la...
ORGANISM(S): Homo sapiens 
2026-06-29 | GSE290281 | GEO
Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection
Alternative polyadenylation (APA) is a widespread mechanism of gene regulation that generates transcript isoforms with distinct 3' ends. While several RNA-binding proteins (RBPs) are known to regulate APA, the roles of the vast majority of RBPs in this process remain poorly characterized. Using a la...
ORGANISM(S): Homo sapiens 
2026-06-29 | GSE290282 | GEO
Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection [eCLIP]
Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection [RNA-Seq]
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