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TranscriptomicsAntioxidants Accelerate Lung Cancer Progression in Mice
Antioxidants are widely used to protect cells from damage induced by reactive oxygen species (ROS). The concept that antioxidants can help fight cancer is deeply rooted in the general population, promoted by the food supplement industry, and supported by some scientific studies. However, clinical tr...
ORGANISM(S): Mus musculus 
2014-01-31 | E-GEOD-52594 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of intestinal tissue samples from germ-free and conventionally raised mice which are either wild-type or Myd88-/-
Whole-transcriptome survey of gene expression differences between germ-free (GF) and conventionally raised (CONV-R) mice. To assess the role of toll-like receptor signalling, both wild-type and Myd88 -/- mice were used. Four different tissues were harvested from 20 mice (5 WT CONV-R, 5 Myd88 -/- CON...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-17438 | biostudies-arrayexpress
TranscriptomicsTranscriptomic characterization of the human cell cycle in individual unsynchronized cells
Here, we profiled transcription across the cell cycle in single human myxoid liposarcoma cells, without prior synchronization. Flourescence-activated cell sorting was used to infer G1, S or G2/M cell cycle stages after staining cells for DNA content. Single-cell RNA-sequencing was performed accordin...
ORGANISM(S): Homo sapiens 
2017-11-09 | E-MTAB-6142 | biostudies-arrayexpress
TranscriptomicsShort-term exposure to effluent from bulk drug industries
The Patancheru area near Hyderabad in India is recognized as a key link in the global supply chain for many bulk drugs. A central treatment plant receives wastewater from about 90 different manufacturers and the resulting complex effluent has contaminated surface, ground and drinking water in the re...
ORGANISM(S): Rattus norvegicus 
2012-09-01 | E-GEOD-23983 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of 53 tissue samples from germ-free and conventionally raised mice
Whole-transcriptome survey of gene expression differences between germ-free (GF) and conventionally raised (CONV-R) mice. To assess the role of toll-like receptor signalling, both wild-type and Myd88 -/- mice were used. Three different tissues were harvested from 20 mice (5 WT CONV-R, 5 Myd88 -/- CO...
ORGANISM(S): Mus musculus 
2014-01-31 | E-GEOD-31115 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human umbilical vein endothelial cells treated with valproic acid
Valproic acid (VPA) is a short-chain fatty acid used in the treatment of epilepsy and also considered to be an epigenetic modifier by functioning as a histone deacetylase (HDAC)-inhibitor. The aim of this study was to search for gene altered by VPA in human endothelial cells. Human umbilical vein en...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-23909 | biostudies-arrayexpress
MetabolomicsLarge-scale non-targeted plasma metabolomics in the Uppsala Longitudinal Study of Adult Men
The Uppsala Longitudinal Study of Adult Men (ULSAM) study is an ongoing, longitudinal, epidemiologic study started in 1970 and based on men born between 1920 and 1924 in Uppsala, Sweden which were invited to participate at age 50 (N=2,841) [PMID: 9484991]; 81.7% (N=2,322) participated. Individuals w...
2015-03-23 | MTBLS124 | MetaboLights
MetabolomicsLarge-scale non-targeted serum metabolomics in the Prospective Investigation of the Vasculature in Uppsala Seniors
The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) is a community-based study where all men and women at age 70 living in Uppsala, Sweden were invited to participate in 2001. The 1,016 participants (50% women) have been extensively phenotyped. In March 2006 a reinvesigation ...
2014-08-30 | MTBLS90 | MetaboLights
ProteomicsProteome characterization of Breast Cancer Cell lines
Protein profiling of 18 breast cancer cell lines in triplicates using TMT10-plex.
ORGANISM(S): Homo Sapiens (human) 
2020-07-04 | PXD013276 | JPOST Repository
ModelsMardinoglu2015 - Tissue-specific genome-scale metabolic network - White fat
Mardinoglu2015 - Tissue-specific genome-scale metabolic network - White fat This model is described in the article: The gut microbiota modulates host amino acid and glutathione metabolism in mice. Mardinoglu A, Shoaie S, Bergentall M, Ghaffari P, Zhang C, Larsson E, Bäckhed F, N...
2015-11-04 | MODEL1509220026 | BioModels
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