Sort   by:  
 Page size 
MetabolomicsTargeted plasma metabolomics combined with machine learning for the diagnosis of acute SARS-CoV-2

The routine clinical diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely restricted to real-time reverse transcription polymerase chain reaction (RT-qPCR), and tests that detect SARS-CoV-2 nucleocapsid antigen. Given the diagnostic delay and suboptimal sensitivity...

2024-08-26 | MTBLS6739 | MetaboLights
ModelsSmith2011_HumanHeartMitochondrian_MetabolicModel
This model is from the article: A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle. Smith AC, Robinson AJ. BMC Syst Biol. 2011 Jun 29;5(1):102. 21714867 , Abstract: ...
2005-01-01 | MODEL1106160000 | BioModels
TranscriptomicsTranscriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy
The corneal endothelium plays a primary role in maintaining corneal homeostasis and clarity, and must be surgically replaced with allogenic donor corneal endothelium in the event of visually significant dysfunction. However, a worldwide shortage of donor corneal tissue has led to a search for altern...
ORGANISM(S): Homo sapiens 
2015-09-04 | E-GEOD-65991 | biostudies-arrayexpress
UnknownTemperature-Controlled Locally Excited and Twisted Intramolecular Charge-Transfer State-Dependent Fluorescence Switching in Triphenylamine-Benzothiazole Derivatives.
Not available
S-EPMC6648163 | biostudies-literature
GenomicsIdentification of Transcription Factor CEH-26::GFP Binding Regions in LE
modENCODE_submission_3068 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2012-05-07 | E-GEOD-37798 | biostudies-arrayexpress
UnknownImpact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer.
Not available
S-EPMC5903999 | biostudies-literature
TranscriptomicsIdentification of Potentially Pathogenic Variants in the Posterior Polymorphous Corneal Dystrophy 1 Locus
Purpose: To identify the genetic basis of posterior polymorphous corneal dystrophy 1 (PPCD1). Methods: Next-generation sequencing was performed on DNA samples from 4 affected and 4 unaffected members of a previously reported family with PPCD1 linked to chromosome 20 between D20S182 and D20S195. Cus...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-72617 | biostudies-arrayexpress
TranscriptomicsPosterior Amorphous Corneal Dystrophy Is Associated with a Deletion of Small Leucine-rich Proteoglycans on Chromosome 12
Posterior amorphous corneal dystrophy (PACD) is a rare, autosomal dominant disorder affecting the cornea and iris. After next-generation sequencing of the family in which linkage analysis identified a chromosomal locus for PACD on 12q21.33 failed to yield a pathogenic mutation, array-based copy numb...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-50573 | biostudies-arrayexpress
ProteomicsReprogramming the Lipid Peroxidation Product 4-ONE as a Chemoselective Cleavable Crosslinker
Nature builds and stabilizes proteins through covalent biological glues, yet the logic and traceability of metabolite-driven crosslinking remain obscure. Here we reprogram the lipid peroxidation product 4-oxo-nonenal (4-ONE) into a metabolite-derived Cys-Lys biological glue and mass-cleavable crossl...
ORGANISM(S): Homo sapiens (Human) 
2026-06-22 | PXD077820 | Pride
4-one Peroxidation Mass spectrometry Crosslink Lipid 
ProteomicsReprogramming the Lipid Peroxidation Product 4-ONE as a Chemoselective Cleavable Crosslinker
Nature builds and stabilizes proteins through covalent biological glues, yet the logic and traceability of metabolite-driven crosslinking remain obscure. Here we reprogram the lipid peroxidation product 4-oxo-nonenal (4-ONE) into a metabolite-derived Cys-Lys biological glue and mass-cleavable crossl...
ORGANISM(S): Homo sapiens (Human) 
2026-06-22 | PXD077887 | Pride
4-one Peroxidation Mass spectrometry Crosslink Lipid 
Sort   by:  
 Page size