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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
UnknownDysbiotic microbiome variation in colorectal cancer patients is linked to lifestyles and metabolic diseases.
Not available
S-EPMC9883847 | biostudies-literature
ProteomicsAffinity Purification experiments for 24 human Bromodomain proteins involved in DNA repair and genome integrity (part 1 of 2).
Bromodomain proteins (BRD) are key chromatin regulators of genome function and stability, as well as therapeutic targets in cancer. In our associated publication (doi:10.1101/gad.331231.119) we systematically delineate the contribution of human BRD proteins for genome stability and DNA double-strand...
ORGANISM(S): Homo sapiens (Human) 
2019-12-12 | PXD016700 | Pride
R-loops Dna repair Human Bromodomain Chromatin Ap-ms Dna damage response Homologous recombination 
ProteomicsAffinity Purification experiments for 24 human Bromodomain proteins involved in DNA repair and genome integrity (part 2 of 2)
Bromodomain proteins (BRD) are key chromatin regulators of genome function and stability, as well as therapeutic targets in cancer. In our associated publication (doi:10.1101/gad.331231.119) we systematically delineate the contribution of human BRD proteins for genome stability and DNA double-strand...
ORGANISM(S): Homo sapiens (Human) 
2019-12-12 | PXD016673 | Pride
R-loops Dna repair Human Bromodomain Chromatin Ap-ms Dna damage response Homologous recombination 
MetabolomicsNitisinone’s mosquitocidal properties hold promise for malaria control

Nitisinone’s mosquitocidal properties hold promise for malaria control

2025-06-16 | MTBLS11617 | MetaboLights
UnknownPhase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors.
Not available
S-EPMC7845944 | biostudies-literature
MetabolomicsComparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights
UnknownSignificant improvement in survival after allogeneic hematopoietic cell transplantation during a period of significantly increased use, older recipient age, and use of unrelated donors.
Not available
S-EPMC3691359 | biostudies-literature
UnknownTmax Volumes Predict Final Infarct Size and Functional Outcome in Ischemic Stroke Patients Receiving Endovascular Treatment.
Not available
S-EPMC9322332 | biostudies-literature
GenomicHepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C)

Reprinted from http://www.haltctrial.org/

Purpose

The Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) Trial is a randomized controlled trial designed to evaluate the safety and efficacy of long-term use of pegylated inte...

phs000430 | dbGaP
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