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ProteomicsLC-MSMS analysis of API5-FGF2 interactome
We determined the crystal structure of the complex, and identified critical residues driving the protein interaction.
ORGANISM(S): Homo sapiens (Human) 
2020-04-23 | PXD013517 | Pride
Lc-ms Api5 Fgf2 
TranscriptomicsWhole transcriptome analyses of six thoroughbred horses before and after exercising using RNA-Seq
We sequenced the whole mRNA of six thoroughbred horse (Equus caballus) blood and muscle tissues before and after exercising, generating a total of 1.3 billion short reads with 90-bp pair-end sequences from 24 samples. Comparing with current genome annotation, we identified 32,361 unigene clusters sp...
ORGANISM(S): Equus caballus 
2013-05-01 | E-GEOD-37870 | biostudies-arrayexpress
ProteomicsEnhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
Ca2+ overload-induced mitochondrial dysfunction is considered as a major contributing factor in the pathogenesis of alcohol-associated liver disease (ALD). However, the initiating factors that drive mitochondrial Ca2+ accumulation in ALD remain elusive. Here, we demonstrate that an aberrant increas...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039478 | Pride
Ptm Mitochondrial dysfunction Pdk4 Grp75 Lc-ms/ms Alcohol-associated liver disease 
TranscriptomicsChronic low-dose-irradiation of Drosophila melanogaster larvae induces gene expression changes and enhances locomotive behavior
Although radiation effects have been extensively studied, the biological effects of low-dose radiation (LDR) are controversial. This study investigates LDR-induced alterations in locomotive behavior and gene expression profiles of Drosophila melanogaster. We measured locomotive behavior using larval...
ORGANISM(S): Drosophila melanogaster 
2014-09-26 | E-GEOD-61759 | biostudies-arrayexpress
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