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ProteomicsMonomethylation of cytosolic 5’-nucleotidase 1A (cN1A) and its role in inclusion body myositis autoantigenicity
Inclusion body myositis (IBM) is a progressive muscle disease characterized by protein accumulation and anti-cN1A autoantibodies. This study aimed to identify post-translational modifications (PTMs) of cN1A in human skeletal muscle to understand its pathophysiological role. Using immunoaffinity puri...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD075326 | Pride
Monomethylation Ptm Inclusion body myositis Skeletal muscle Autoantibodies Cn1a Lc-ms/ms 
ProteomicsDecoding isozyme-specific substrate recognition in protein arginine deiminases by in vitro proteome-wide citrullination mapping
Protein arginine deiminases (PADs) convert arginine to citrulline, altering protein structure and function. Of the five human isozymes, PAD1–4 are catalytically active with distinct tissue-specificities, yet isozyme-specific substrate recognition remains poorly defined. Here, we provide a systematic...
ORGANISM(S): Homo sapiens (Human) 
2026-04-22 | PXD071247 | Pride
ProteomicsProtein citrullination in human tissues
Citrullination is a post-translational modification of arginine catalyzed by five peptidylarginine deiminases (PADs) in humans. The loss of a positive charge may cause structural or functional alterations and while the modification has been linked to several diseases including rheumatoid arthritis a...
ORGANISM(S): Homo sapiens (Human) 
2018-04-04 | PXD008970 | Pride
Citrullination Post-translational modification Peptidylarginine deiminase Human proteome Synthetic peptides 
ProteomicsData, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. To facilitate proteomic research on SARS-CoV-2, we presents deep-scale proteomes of common cell lin...
ORGANISM(S): Homo sapiens (Human) Cercopithecus aethiops (Green monkey) (Grivet) Chlorocebus sabaeus 
2020-07-15 | PXD019645 | Pride
Sars-cov-2 Vero e6 Stable isotope labeling Clinical proteomics Parallel reaction monitoring Infectome Covid-19 Ace2 
ProteomicsDeep Proteomic and Phosphoproteomic Profiling in Proteasome Inhibitor-Resistant Multiple Myeloma
Proteasome inhibitors (PIs) are frontline therapies for multiple myeloma (MM). Although MM patients initially respond to PIs, resistance frequently emerges. While clinical PIs primarily target the same proteasomal catalytic subunit (PSMB5), the extent to which resistance mechanisms are shared among ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-15 | PXD077254 | Pride
Phosphoproteomics Proteasome inhibitor resistance Quantitative proteomics Multiple myeloma 
ProteomicsData, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. To facilitate proteomic research on SARS-CoV-2, we presents deep-scale proteomes of common cell lin...
ORGANISM(S): Chlorocebus Sabaeus (ncbitaxon:60711) Chlorocebus Aethiops (ncbitaxon:9534) Homo Sapiens (ncbitaxon:9606) 
2020-07-17 | MSV000085774 | MassIVE
ProteomicsIlluminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics-2
Kinase inhibitors (KIs) are important cancer drugs but often display polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To investigate more systematically how the cellu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-29 | MSV000093533 | MassIVE
ProteomicsIlluminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics
Kinase inhibitors (KIs) are important cancer drugs but often display polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To investigate more systematically how the cellu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-11 | MSV000091043 | MassIVE
ProteomicsData, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to better understand how the virus works and to find out how it may be tackled. The number of manuscripts on pre-print servers is soaring and peer-reviewed publications using mass...
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
2020-09-11 | PXD019680 | panorama
ProteomicsMass spectrometry-based draft of the mouse proteome
Quantitative draft map of the proteomes of 41 healthy tissues of the animal model Mus musculus and a panel of 66 murine pancreatic ductal adenocarcinoma cell lines and. Our in-depth analysis provides evidence for proteins encoded by >16,000 genes (~76% of the total annotated protein-coding genes), w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-07-09 | MSV000089856 | MassIVE
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