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UnknownHigh-throughput dense reconstruction of cell lineages.
Not available
S-EPMC6936253 | biostudies-literature
MetabolomicsSubcutaneous white adipose tissue-derived extracellular vesicle maintains intestinal homeostasis via IgA biosynthesis in aging mice

To identify the potential iWAT-derived adipokines that regulate intestinal IgA biosynthesis, we conducted untargeted metabolomics in the serum of iFR and iSham mice. A total of 214 differential abundant metabolites were identified (log2FC >1 or <-1 and adjusted p-value <0.05) between the...

2025-09-05 | MTBLS12800 | MetaboLights
TranscriptomicsTranscription profiling of 25 breast cancer cell lines grown in 2D and 3D tissue culture conditions
A comparison of gene expression profiles for 25 breast cancer cell lines grown in 2D and 3D tissue culture conditions
ORGANISM(S): Homo sapiens 
2007-05-02 | E-TABM-244 | biostudies-arrayexpress
ProteomicsGlobal Phosphoproteomics of BRCA1-deficient mammary tumors in genetic mouse models
The aim of the study is to identify differences in the global phosphoproteome across a BRCA1-deficient mouse mammary tumor panel. We have matched PARPi-naive and PARPi-resistant tumors, in which resistance was induced in vivo (mice bearing tumors were treated with PARPi untill the tumors stopped res...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-06 | PXD032007 | Pride
Brca1 Global phosphoproteomics Rad51 foci Parpi Label-free Dna damage response Gemm 
TranscriptomicsGlobal gene expression profiles in Oct4-knockdown and Ccna2-knockdown mouse embryos.
Gene regulation at the maternal-embryonic transition in the pre-implantation mouse embryo is not well understood. We knock down Ccna2 to establish proof-of-concept that antisense morpholino oligonucleotides can be used to target specific genes. We applied this strategy to study Oct4 and discovered...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-13981 | biostudies-arrayexpress
ProteomicsPhosphoproteomics of truncated FGFR2, a clinically actionable oncogene in multiple cancers
Somatic hotspot mutations and structural amplifications and fusions affecting fibroblast growth factor receptor 2 (FGFR2) occur in multiple cancer types. However, clinical responses to FGFR inhibitors (FGFRi) have remained variable, emphasizing a need to better understand which FGFR2 alterations are...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-06 | PXD031711 | Pride
Cancer Fgfr2 Imac Mouse model Ptyrip Label-free Phosphoproteomics 
TranscriptomicsDiscovery of consensus gene signature and intermodular connectivity defining self-renewal of human embryonic stem cells
Comparison of gene expression signatures in undifferentiated hESCs against differentiated embryoid bodies to identify key signatures defining self-renewal of hESCs. Using H1 and H9 hESC lines, we performed gene expression microarray analysis (Affymetrix Human Genome U133 Plus 2.0 Array) and analyzed...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54186 | biostudies-arrayexpress
GenomicsBC Cancer, part of the Provincial Health Services Authority, Technology Development Office, Data Access Committee (PHSA TDO DAC)
Access to data generated by BCCA is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.
EGAC00000000011 | EGA
TranscriptomicsAgilent 244A aCGH array for comparison of lung tumor CNA to high-throughput sequencing data
1 lung tumor was profiled for copy-number alterations with the high-resolution Agilent 244A aCGH Array. One lung tumor sample were assayed on the Agilent Human Genome CGH 244A Microarrays with the intent of comparing the genomic alterations reported by the array platform with those reported by high-...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20574 | biostudies-arrayexpress
TranscriptomicsAssessment of mutation on expression levels
One lung tumor and its adjacent normal were profiled for expression levels with the Affymetrix HGU133 plus 2.0 array. One lung tumor sample and its adjacent normal were assayed on the Affymetrix HG-U133 plus 2.0 array to assess the effects of mutation on expression.
ORGANISM(S): Homo sapiens 
2011-02-21 | E-GEOD-20578 | biostudies-arrayexpress
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