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ProteomicsHuman Placenta profilling LTQ-OrbiTrap
Profilling normal human placantal proteomes using LTQ-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083950 | MassIVE
ProteomicsRibonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules
Circular RNAs (circRNAs) accumulate with age, but their functional impact on aging remains elusive. In this study, we reveal a mechanism by which ribonuclease κ (RNASEK) prevents age-dependent circRNA accumulation by promoting its degradation. Through a genetic screen targeting ribonucleases, we ide...
ORGANISM(S): Caenorhabditis Elegans 
2026-01-15 | PXD073097 |
ProteomicsHuman Placenta profilling LTQ-OrbiTrap
Profilling normal human placantal proteomes using LTQ-OrbiTrap
ORGANISM(S): Homo sapiens (Human) 
2015-05-26 | PXD000754 | Pride
Placenta Normal Human C-hpp 
ProteomicsInhibition of Alternative Complement Pathway May Cause Secretion of Factor B, Enabling an Early Detection of Pancreatic Cancer
This study aims to elucidate the cellular mechanisms underlying the secretion of factor B (CFB), recognized for its dual role as an early biomarker of pancreatic ductal adenocarcinoma (PDAC) and as the initiating substrate for the alternative complement pathway (ACP), a crucial component of the inna...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD047043 | Pride
Complement factor b Proteomics Adrenomedullin Alternative pathway Pancreatic ductal adenocarcinoma Cancer biomarker Complement factor h 
ProteomicsIdentification of ALDH6A1 as a Potential Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome
Various liver diseases, including hepatocellular carcinoma (HCC), have been linked to mitochondrial dysfunction, a condition characterized by abnormal levels of nitric oxide (NO) and reactive oxygen species (ROS). In this study, we subjected the human liver mitochondrial proteome to an extensive qua...
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD014252 | Pride
Aldh6a1 Nitric oxide Hepatocellular carcinoma Reactive oxygen species Mitochondria 
ProteomicsLung cancer and Normal Lung Tissue LC-MS/MS
The Chromosome-centric Human Proteome Project (C-HPP) was recently initiated as an international collaborative effort. Our team adopted chromosome 9 (Chr 9) and performed a bioinformatics and proteogenomic analysis to catalog Chr 9-encoded proteins from normal tissues, lung cancer cell lines and lun...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083969 | MassIVE
ProteomicsIdentification of Missing Proteins in Human Olfactory Epithelial Tissue by Liquid Chromatography-Tandem Mass Spectrometry
We performed proteomic analyses of human olfactory epithelial tissue to identify missing proteins using liquid chromatography-tandem mass spectrometry. Using a next-generation proteomic pipeline with a <1.0% false discovery rate at the peptide and protein levels, we identified 3,731 proteins, among ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-12 | MSV000086444 | MassIVE
ProteomicsnextPP for chromosome-based proteomic research using neXtProt and GENCODE databases
In this study, we introduce a streamlined pipeline using customized and concatenated GENCODE and neXtProt databases with controlled false discovery rate (FDR) for finding GENCODE ASVs and missing proteins while mapping onto single amino acid variants (SAAVs) from Hippocampal dataset.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-25 | MSV000081385 | MassIVE
TranscriptomicsGenomic copy number alterations as predictive markers of systemic recurrence in breast cancer
Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess copy number changes in 31 pairs of clinicopathologically well matched recurred / nonrecurred breast cancer tissues. Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess c...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10128 | biostudies-arrayexpress
ProteomicsIntegrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues
Patient tissue samples raw data: ERBB2 positive and ERBB2 negative
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-08-05 | MSV000079211 | MassIVE
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