Sort   by:  
 Page size 
Self-renewal circuitry in embryonic stem (ES) cells is increasingly defined. How the robust pluripotency programme is dissolved to enable fate transition is less appreciated. We developed a forward genetic approach using haploid ES cells. We created libraries of transposon integrations and screened ...
ORGANISM(S): Mus musculus 
Cell fate transitions depend on balanced rewiring of transcription and translation programmes to enable ordered developmental progression. We identified a feedback loop between nonsense-mediated mRNA decay (NMD) and translation initiation, in which NMD controls the translation initiation factor Eif4...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-09 | PXD019588 | Pride
Our aim was to identify Regenerating islet-derived (REG proteins in dogs. We annotated REG-family members in the canine genome and proteome, and identified one member of the REG3 subfamily, consequently termed REG3E by the Vertebrate Gene Nomenclature Committee. We verified REG3E gene expression usi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-10-17 | PXD035694 | Pride
Sort   by:  
 Page size