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TranscriptomicsVIA of EM CD8 T cells in vaccinated monkeys
The goal of an effective AIDS vaccine is to generate immunity that will prevent HIV-1 acquisition. Despite limited progress towards this goal, renewed optimism has followed the recent success of the RV144 vaccine trial in Thailand. However, the lack of complete protection in this trial suggests th...
ORGANISM(S): Macaca mulatta 
2012-06-14 | E-GEOD-35628 | biostudies-arrayexpress
ProteomicsNanomaterials trigger functional responses in primary human immune cells
Targeting the immune system with nanoparticles (NPs) to deliver immunomodulatory molecules emerged as a solution to address intra-tumoral immunosuppression and enhance therapeutic response. While the potential of nanoimmunotherapies in reactivating immune cells has been evaluated in several preclini...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD056695 | Pride
Nanomaterials  human lymphocytes  nlc-ms/ms  sp3-spe  differential analysis 
ProteomicsRal GTPases promote metastasis by controlling biogenesis and organotropism of exosomes
Cancer extracellular vesicles (EVs) mainly exert pro-tumoral functions by changing the phenotypes of stromal cells to the benefit of tumor growth and metastasis. In particular, they shuttle to distant organs and seed pre-metastatic niches facilitating subsequent colonization by circulating tumor cel...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020180 | Pride
Human Ral Nanolcmsms prostar maxquant Extracellular vesicles 
ProteomicsPeripheral positioning of lysosomes supports melanoma aggressiveness
Peripheral positioning of lysosomes supports melanoma aggressiveness
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD042007 | Pride
Exosomes 
TranscriptomicsDC populations incubated with rAd5, rAd28, rAd35, TLR7/8-ligand, or unexposed
Recombinant adenovirus vectors (rAds) are being investigated as vaccine delivery vehicles in pre-clinical and clinical studies. rAds constructed from different serotypes differ in receptor usage, tropism, and ability to activate cells, aspects of which likely contribute to their different immunogeni...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-37128 | biostudies-arrayexpress
UnknownEffect of weight-adjusted intermediate-dose versus fixed-dose prophylactic anticoagulation with low-molecular-weight heparin on venous thromboembolism among noncritically and critically ill patients with COVID-19: the COVI-DOSE trial, a multicenter, randomised, open-label, phase 4 trial.
Not available
S-EPMC10250778 | biostudies-literature
UnknownEffect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical Trial.
Not available
S-EPMC7577198 | biostudies-literature
Unknown74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis.
Not available
S-EPMC2911915 | biostudies-literature
UnknownHIV Infection and Long-Term Residual Cardiovascular Risk After Acute Coronary Syndrome.
Not available
S-EPMC7660787 | biostudies-literature
UnknownHIV-related excess mortality and age-related comorbidities in patients with HIV aged ≥60: a relative survival analysis in the French Dat'AIDS cohort.
Not available
S-EPMC6352790 | biostudies-literature
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