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ProteomicsDetermination of the mechanisms of hepatotoxicity induced by chlordecone and chlordecol from primary human hepatocytes cells and proteomic analyzes
Chlordecone (CLD) is a pesticide used to control the banana weevill in the French West Indies from 1970 to 1993. Despite its ban in the 90s, the highly persistence of CLD and contamination of the food webs raised tremendous concern for public health [1]. CLD can induce reprotoxic, neurotoxic and hep...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD043763 | Pride
Chlordecol Pesticide Metabolism Kepone Proteomics Multi-omics Metabolomics Septins Mitochondrion Liver Toxicology Chlordecone 
ProteomicsDetermination of the mechanisms of hepatotoxicity induced by chlordecone and chlordecol from HepaRG cells and proteomic analyzes
Chlordecone (CLD) is a pesticide used to control the banana weevill in the French West Indies from 1970 to 1993. Despite its ban in the 90s, the highly persistence of CLD and contamination of the food webs raised tremendous concern for public health [1]. CLD can induce reprotoxic, neurotoxic and hep...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD043683 | Pride
Chlordecol Metabolism Heparg Pesticide Kepone Proteomics Multi-omics Metabolomics Septins Toxicology. Mitochondrion Liver Chlordecone 
ProteomicsVitamin C-induced breast cancer cell death is associated with remodeling the redox state of cysteine-containing proteins involved in translation and cell cycle progression
Recent studies show vitamin C (VitC) pro-oxidant properties at high pharmacological concentrations which favor repurposing VitC as an anti-cancer therapeutic agent. However, redox-based anticancer properties of different forms of VitC are yet partially understood. We examined the difference between ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-16 | PXD013833 | Pride
Breast cancer Ascorbic acid Vitamin c Dehydroascorbic acid Oxidative stress Redoxome 
UnknownC-C Bond Cleavage Approach to Complex Terpenoids: Development of a Unified Total Synthesis of the Phomactins.
Not available
S-EPMC7771649 | biostudies-literature
UnknownOuter-sphere effects on the O2 sensitivity, catalytic bias and catalytic reversibility of hydrogenases.
Not available
S-EPMC11023054 | biostudies-literature
no omics definedTranscription profiling of Medicago truncatula radicles incubated in polyethylene glycol solution and embryos at different time points after pollination to study dessication tolerance
Time course of the transcriptome of desiccation-sensitive 2.7-2.9 mm-long radicles of Medicago truncatula seeds at different time points during incubation in a polyethylene glycol (PEG) solution at -1.7 MPa and 10°C, resulting in a gradual re-establishment of desiccation tolerance. Gene profiling wa...
ORGANISM(S): Medicago truncatula 
2006-04-30 | E-MEXP-664 | biostudies-arrayexpress
UnknownLOU/c/jall rat as a model of resilience in the context of streptozotocin-induced cognitive impairment.
Not available
S-EPMC12571741 | biostudies-literature
UnknownNovel tRNA Synthetase Inhibitors Increase Healthspan, Lifespan, and Autophagic Flux in C. elegans.
Not available
S-EPMC12839378 | biostudies-literature
TranscriptomicsDevelopmental transcriptomics of the model caterpillar fungus Cordyceps militaris
The RNA-Seq technique was used to investigate the differentially transcribed genes of the caterpillar fungus Cordyces militaris. It was calculated that >63% of total annotated genes were expressed, including >55% of putative pathogen-host interaction genes. Overall, the fruiting-body development and...
ORGANISM(S): Cordyceps militaris 
2011-11-08 | E-GEOD-28001 | biostudies-arrayexpress
UnknownRedox modifications of cysteine-containing proteins, cell cycle arrest and translation inhibition: Involvement in vitamin C-induced breast cancer cell death.
Not available
S-EPMC6831881 | biostudies-literature
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