Sort   by:  
 Page size 
Kaposi’s Sarcoma associated herpesvirus (KSHV) is an oncogenic human virus and leading cause of mortality in HIV infection. Reactivation of KSHV from latent to lytic stage infection initiates a cascade of viral gene expression, and here we show how these changes remodel the host cell proteome to ena...
ORGANISM(S): Homo sapiens (Human) Human gammaherpesvirus 8 
2021-08-23 | PXD021387 | Pride
Kaposi’s Sarcoma associated herpesvirus (KSHV) is an oncogenic human virus and leading cause of mortality in HIV infection. Reactivation of KSHV from latent to lytic stage infection initiates a cascade of viral gene expression, and here we show how these changes remodel the host cell proteome to ena...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 8 strain rKSHV.219 
2022-05-26 | PXD017365 | Pride
Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases. Although the replacement of lost endogenous cells was originally proposed as the primary healing mechanism of NSC grafts, it is now clear that transplanted NSCs operate via multiple mec...
ORGANISM(S): Homo sapiens (Human) 
2021-03-16 | PXD024368 | Pride
SARS-CoV2 is recognised the antagonise the interferon response, and functioning interferon responses are critical in determining the severity of disease. However, whether the virus antagonises cellular immunity has not been determined. We used quantitative plasma membrane proteomics in lung epitheli...
ORGANISM(S): Homo sapiens (Human) 
2022-05-26 | PXD025000 | Pride
Critical cell surface immunoreceptors downregulated by HIV have previously been identified using non-systematic, candidate approaches. To gain a comprehensive, unbiased overview of how HIV infection remodels the T-cell surface, we took a distinct, systems-level, quantitative proteomic approach. HIV ...
ORGANISM(S): Homo sapiens (Human) 
2015-11-09 | PXD002934 | Pride
HIV accessory proteins manipulate host factors to evade cellular restriction and enhance viral replication. We used multiplex tandem mass tag (TMT)-based whole cell proteomics to gain a comprehensive, time-based overview of proteins and processes subverted during HIV infection. To make specific func...
ORGANISM(S): Homo sapiens (Human) 
2016-09-29 | PXD004187 | Pride
Sort   by:  
 Page size