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UnknownData on quantification of signaling pathways activated by KIT and PDGFRA mutants.
Not available
S-EPMC5107687 | biostudies-literature
ProteomicsThe ITM2B-associated retinal dystrophy mutation modifies BRI23 peptide interactions in the human retina
BRI23, composed of the 23 last amino acids of the integral transmembrane protein 2B (ITM2B) C-terminus, is associated with several neurodegenerative diseases, including retinal dystrophy (RD) and familial dementia. Its role in the retina remains poorly understood. This study provides a comprehensive...
ORGANISM(S): Homo sapiens (Human) 
2025-07-25 | PXD060682 | Pride
Bri23 Retina Retinal dystrophy Protein interactions Itm2b 
TranscriptomicsIdentification of common features proffered by KIT and PDGFRA mutations in gastro-intestinal stromal tumors
Mutations in KIT proto-oncogene receptor tyrosine kinase (KIT) or platelet derived growth factor receptor alpha (PDGFRA) are responsible for more than 85% of the gastrointestinal stromal tumors (GIST). The introduction of imatinib in the therapy scheme of GIST revolutionized the patient outcome. Unf...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4548 | biostudies-arrayexpress
UnknownA polymeric diet rich in transforming growth factor beta 2 does not reduce inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal rats.
Not available
S-EPMC7731574 | biostudies-literature
UnknownStructural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.
Not available
S-EPMC3173127 | biostudies-literature
ProteomicsLRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface
Synapses are organized into nanocolumns that control neurotransmission efficacy through precise alignment of postsynaptic AMPARs and presynaptic release sites. How these are trans-synaptically arranged remains elusive, despite evidence involving adhesion proteins. Highly enriched and confined at syn...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-18 | PXD054623 | Pride
Synapse Lrrtm 
UnknownIn vitro efficacy of potentiated egg yolk powder against Campylobacter jejuni does not correlate with in vitro efficacy.
Not available
S-EPMC6405129 | biostudies-literature
UnknownLack of Evidence That Selenium-Yeast Improves Chicken Health and Modulates the Caecal Microbiota in the Context of Colonization by Campylobacter jejuni.
Not available
S-EPMC5355472 | biostudies-literature
UnknownPhenotypic and Transcriptomic Responses of Campylobacter jejuni Suspended in an Artificial Freshwater Medium.
Not available
S-EPMC5611540 | biostudies-literature
UnknownLRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface.
Not available
S-EPMC11470055 | biostudies-literature
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