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ProteomicsYeast genetic codes - Endogenous Stochastic Decoding of the CUG Codon by Competing Ser- and Leu-tRNAs in Ascoidea asiatica
While the “universal” genetic code is now known not to be universal, and stop codons can have multiple meanings, one regularity remains, namely that for a given sense codon there is a unique translation. Examining CUG usage in yeasts that have transferred CUG away from leucine, we here report the fi...
ORGANISM(S): Saccharomycopsis fibuligera Ascoidea rubescens DSM 1968 Clavispora lusitaniae ATCC 42720 Babjeviella inositovora NRRL Y-12698 Saccharomycopsis malanga Ascoidea asiatica Nakazawaea peltata 
2018-06-13 | PXD009494 | Pride
Ascoidea Clavispora Saccharomycopsis Nakazawaea Babjeviella 
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
ProteomicsIncorporation of photo-amino acids in HeLa cells
In order to assess the efficiency of photo-labeling, total HeLa cell lysates treated with photo-amino acids were subjected to proteome analysis.
ORGANISM(S): Homo sapiens (Human) 
2017-04-10 | PXD005346 | Pride
Hela cells Incorporation Photo-methionine Photo-leucine Orbitrap fusion 
UnknownHuman isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Not available
S-EPMC10617216 | biostudies-literature
UnknownQuantitative vibrational dynamics of the metal site in a tin porphyrin: an IR, NRVS, and DFT study.
Not available
S-EPMC3787516 | biostudies-literature
ProteomicsIntegration of JAK/STAT receptor-ligand trafficking, signalling and gene expression in Drosophila melanogaster cells
The JAK/STAT pathway is an essential signalling cascade required for multiple processes during both development and for adult homeostasis. A key question in understanding this pathway is how it is regulated in different cell contexts. Here we have examined how endocytic processing contributes to sig...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-09-29 | PXD020719 | Pride
Endocytosis Phosphorylation Drosophila Jak/stat signalling Lc-ms/ms 
TranscriptomicsRole of ICOS:ICOSL interaction in acute GVHD
Inducible co-stimulator (ICOS) interaction with its ligand (ICOSL) is involved in several T cell effector functions. While blockade of ICOS:ICOSL interaction in chronic graft versus host disease (GVHD) seems benefi cial, results for acute GVHD remain controversial. To further elucidate its role in a...
ORGANISM(S): Mus musculus 
2009-09-14 | E-GEOD-17995 | biostudies-arrayexpress
TranscriptomicsMycobacterium bovis-BCG vaccination induces a specific pulmonary transcriptome biosignature in mice
In the present study, we applied microarray technology to define a biosignature from the whole genome expression in lung and spleen samples after BCG vaccination and M. bovis infection of BALB/c mice. The aims were two-fold, namely to define biosignatures that could predict vaccine success before ch...
ORGANISM(S): Mus musculus 
2010-07-29 | E-GEOD-21149 | biostudies-arrayexpress
TranscriptomicsTGF-beta/Smad3-dependent gene expression analysis in naive CD4 T cells
Investigation of transcript level modulation in unstimulated and TGF-beta treated (with or without superimposed T-cell receptor and CD28 stimulation) naive CD4 T cells from wild type or Smad3-deficient littermate mice. Smad3 is a critical signaling molecule and transcription factor downstream of TGF...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-40494 | biostudies-arrayexpress
ProteomicsSalt stress in freshwater anaerobic methane-oxidizing archaea
Maider J. Echeveste Medrano and colleagues characterized the physiological and metabolic response of freshwater methanotrophic archaea to salt stress. The study performed metaproteomics, gene expression profiles and dedicated metabolomics to identify the pathways involved in the salt stress response...
ORGANISM(S): Candidatus Methanoperedens nitroreducens 
2024-07-17 | PXD048239 | Pride
Salt stress Methane-oxidizing archaea Shotgun proteomics Metaproteomics 
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