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ProteomicsFACS-Proteomics strategy toward Extracellular Vesicles single-phenotype characterization in biological fluids: insights into the role of Leukocyte-derived EVs in Multiple Sclerosis
The isolation and proteomics characterization of Extracellular Vesicles (EVs) from body fluids represents a stimulating challenge to improve our knowledge of biology, considering the vast heterogeneity in terms of phenotype in vivo. Within a complex and dynamic scenario of EVs isolation and characte...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD049036 | Pride
Leukocyte-derived evs Multiple sclerosis Facs-proteomics Tears 
TranscriptomicsCrosstalk between the effects of extracellular vesicles (Evs) and TNF on U937 human monocyte cell line
Under physiological conditions, extracellular vesicles (EVs) are present simultaneously in the extracellular compartment together with cytokines. Thus, we hypothesized that EVs in combination with cytokines induce different responses of monocyte cells compared to EVs or cytokines alone. Human monocy...
ORGANISM(S): Homo sapiens 
2013-06-19 | E-GEOD-47897 | biostudies-arrayexpress
UnknownFACS-Proteomics strategy toward extracellular vesicles single-phenotype characterization in biological fluids: exploring the role of leukocyte-derived EVs in multiple sclerosis.
Not available
S-EPMC12093873 | biostudies-literature
TranscriptomicsRole of miRNAs in acute kidney injury recovery induced by mesenchymal stromal cells and derived extracellular vesicles.
Phenotypic changes induced by extracellular vesicles (EVs) have been implicated in the recovery of acute kidney injury (AKI) induced by mesenchymal stromal cells (MSCs). miRNAs are potential candidates for cell reprogramming towards a pro-regenerative phenotype. The aim of the present study was to e...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-59958 | biostudies-arrayexpress
UnknownDifferential Interaction of Platelet-Derived Extracellular Vesicles with Leukocyte Subsets in Human Whole Blood.
Not available
S-EPMC5920058 | biostudies-literature
UnknownLeukocyte-Derived Extracellular Vesicles in Blood with and without EpCAM Enrichment.
Not available
S-EPMC6721753 | biostudies-literature
TranscriptomicsHuman iPSC-derived cardiomyocytes under hypoxia/normoxia, treated with bone marrow or cardiac stromal cell extracellular vesicles
RNA-seq was performed on cultured human induced pluripotent cell derived cardiomyocytes (iPSC-CMs). There are four groups, with three samples per group: H1,H2,H3. Negative control. Healthy, normoxic iPSC-CMs D1,D2,D3. Positive control. iPSCs cultured under hypoxic (0-1% O2) for 48h with 2% v/v PBS ...
ORGANISM(S): Homo sapiens 
2024-10-02 | E-MTAB-13966 | biostudies-arrayexpress
UnknownHigh Blood Concentration of Leukocyte-Derived Extracellular Vesicles Is Predictive of Favorable Clinical Outcomes in Patients with Pancreatic Cancer: Results from a Multicenter Prospective Study.
Not available
S-EPMC9562679 | biostudies-literature
ProteomicsPro-inflammatory Beta Cell Small Extracellular Vesicles Induce Beta Cell Failure Through Activation of the CXCL10/CXCR3 Axis in Diabetes
Coordinated communication among pancreatic islet cells is necessary for the maintenance of glucose homeostasis. In diabetes, chronic exposure to pro-inflammatory cytokines has been shown to perturb β-cell communication and function. Compelling evidence has implicated extracellular vesicles (EVs) in ...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-25 | PXD026998 | Pride
Inflammation Β-cell Extracellular vesicles Intercellular communication Cxcl10 Diabetes 
UnknownLongitudinal Trend of Plasma Concentrations of Extracellular Vesicles in Patients Hospitalized for COVID-19.
Not available
S-EPMC8801799 | biostudies-literature
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