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Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
Sperm cells are terminally differentiated cells that are essential for reproduction in sexually reproducing species. Consistent with their highly specialized function, sperm cells harbor a unique proteome containing many proteins not expressed in somatic cells. In contrast, the post-translational la...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2024-12-19 | PXD056661 | Pride

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
Given that ERC1 proteins are enriched on membraneless condensates together with ATG8 proteins prior to autophagosome formation, we hypothesized that ERC1-positive condensates might serve as an assembly site for ATG8 proteins and other adaptors before ATG8 proteins are conjugated onto the phagophore ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-10-07 | PXD067354 | Pride
By employing a proximity labeling approach using Arabidopsis ATG8e tagged with TurboID as bait in atg2-1 background, we discovered a protein family of unknown function, consisting of two homologs (AT4G02880 and AT1G03290). Both proteins contain coil-coiled domains that are predicted to be closely re...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-10-07 | PXD067352 | Pride
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