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ProteomicsStudy on goat sperm by quantitative proteomics technology
The summary file contains summary information for all the raw files processed with a single MaxQuant run. The summary information consists of some MaxQuant parameters, information of the raw file contents, and statistics on the peak detection. Based on this file a quick overview can be gathered on t...
ORGANISM(S): Capra Hircus 
2023-06-22 | PXD043267 |
ProteomicsComparative proteomics of fresh sperm and frozen sperm collected by electric stimulation method and Artificial vagina method
This progect included TMT-based proteomics and PRM proteomics. The study aimed to we aimed to investigate the differential impact of rectal probe electrostimulation and artificial vagina semen collection methods on the quality and the freezing tolerance of goat sperm.
ORGANISM(S): Capra Hircus 
2023-11-29 | PXD047354 |
ProteomicsGlucose depletion enables Candida albicans mating independent of the epigenetic white-opaque switch
The human fungal pathogen Candida albicans can switch stochastically and heritably between a “white” phase and an “opaque” phase. Opaque cells are the mating-competent form of the species whereas white cells are essentially “sterile”. Here, we report that glucose depletion, a common nutrient stress,...
ORGANISM(S): Candida Albicans 
2023-03-03 | PXD040559 |
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Here, we found that R236 methylation of PHGDH promotes its activity and stimulates serine synthesis in hepatocellular carcinoma.
ORGANISM(S): Homo Sapiens 
2022-07-28 | PXD035061 |
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and HCC Growth
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Phosphoglycerate dehydrogenase (PHGDH) is the first rate-limiting enzyme in serine biosynthesis pathway. Here, we analyzed immunoprecipitated PHGDH from human HEK293T cells by liquid ch...
ORGANISM(S): Homo Sapiens 
2022-07-29 | PXD035287 |
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