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MetabolomicsEffects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
Major depressive disorder (MDD), also known as depression, is a state characterized by low mood and aversion to activity. Platycodins Folium (PF) is the dried leaf of Platycodon grandiflorum, with anti-inflammatory and antioxidative activities. Our previous research suggested that PF was rich in fla...
2020-06-03 | MTBLS952 | MetaboLights
UnknownSOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1.
Not available
S-EPMC12209067 | biostudies-literature
ProteomicsBacterial community structure and metabolomic pathways in yak milk and cattle-yak milk during refrigeration: analysis of interspecific differences in dairy spoilage
Raw milk usually needs to be refrigerated at 4℃ before production, and microbial contamination during this process can cause spoilage of refrigerated raw milk. However, there is currently almost no research on plateau characteristic milk (yak milk and cattle-yak milk) (YM and CYM). In this study, si...
ORGANISM(S): Bos Taurus 
2024-03-22 | PXD050886 |
ProteomicsDenitrifying phosphorus removal sludge with heavy metals
DPRS treated by Cd2+, Ni2+ and Cr6+. We look into the differences in metaproteome of treated reactors and the control group, and aim to find the resistance mechanisms of DPRS toward heavy metals
ORGANISM(S): Acidobacteriaceae Bacterium A2-4c Escherichia Coli 
2020-06-10 | PXD019707 |
ProteomicsAntibody-Free Profiling of Lysine Dimethylation via Chemoselective OxidationCoupled Reversible Enrichment
Lysine dimethylation (Kme2) is a critical post-translational modification (PTM), while its comprehensive analysis remains challenging due to low stoichiometry and lack of pan-specific antibodies. Here, we developed an antibody-free proteomics strategy combining selective fluorine-mediated oxidation ...
ORGANISM(S): Homo Sapiens 
2026-05-18 | PXD078472 |
ProteomicsPhosphoproteomic in soleus and biceps femoris muscle
We used phosphoproteomic profiling of slow-twitch (soleus, SOL) and fast-twitch (biceps femoris, BF) muscle to identify differences between these muscle types.
ORGANISM(S): Sus Scrofa Domesticus 
2022-08-16 | PXD036066 |
ProteomicsImpaired O-GlcNAcylation rather than N-glycosylation caused by AtAGM deficiency leads to growth variations in Arabidopsis thaliana
To reveal the function of N-acetylglucosamine phosphate mutase (AGM) and UDP-GlcNAc in Arabidopsis growth, WT and a T-DNA insertional mutant Atagm-2 were used for proteomic analysis.
ORGANISM(S): Arabidopsis Thaliana 
2021-03-25 | PXD024977 |
ProteomicsThe mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
MAVS-Turbo ID IP in HEK293T cells treated with or without SeV
ORGANISM(S): Homo Sapiens 
2020-12-08 | PXD023002 |
ProteomicsOne-Step Chemoenzymatic Labeling and Oxime-Reversible Enrichment for O-GlcNAc Profiling in Oxidative Stress
Chemoenzymatic labeling has greatly advanced O-GlcNAc proteomics, yet existing strategies using azide-modified donors (e.g., UDP-GalNAz) require multi-step click-based workflows that introduce substantial sample loss and limit sensitivity toward low-abundance targets. While recent one-step labeling ...
ORGANISM(S): Homo Sapiens 
2026-01-06 | PXD072723 |
ProteomicsMass Spectrometry analysis of potential proteins interacting with cyclin D1 mutants (T286A or T288A)
Co-IP assays and Proteomics were performed to identify potential E3 ligases interacted with both cyclin D1 T286A and cyclin D1 T288A.
ORGANISM(S): Homo Sapiens 
2024-05-17 | PXD052332 |
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