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ProteomicsChemoproteomic profiling of O-GlcNAcylated proteins and identification of O-GlcNAc transferases in rice
O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a ubiquitous posttranslational modification occurring in both animals and plants. Thousands of proteins along with their O-GlcNAcylation sites have been identified in various animal systems, yet the O-GlcNAcylated proteomes in plants remain po...
ORGANISM(S): Oryza sativa (Rice) 
2023-05-10 | PXD036527 | Pride
O-glcnacylation Hcd pd ethcd Metabolic glycan labeling Plant glycobiology. Rice Chemoproteomic 
ProteomicsN-glycoproteome profiling of rice
Metabolic glycan labeling (MGL) is a technique that utilizes bioorthogonal chemical reporters to investigate protein glycosylation. While this method has been widely used for glycoproteomic profiling in animals, its application in N-glycoproteomic research in crops remains limited and requires furth...
ORGANISM(S): Oryza sativa (Rice) 
2025-05-06 | PXD048132 | Pride
Ms/ms Metabolic glycan labeling N-glycosylation Rice 
UnknownTranscriptomic regulation of the hypothalamic-pituitary axis by GnRH immunization in Xizang sheep.
Not available
S-EPMC12927403 | biostudies-literature
ProteomicsIcariside II restores vascular smooth muscle cell contractile phenotype by enhancing focal adhesion signaling pathway in rat vascular remodeling model
In this work, we investigated the pharmacological effects of ICS-II on VSMC phenotypic transition and reveal the underlying mechanisms through in vivo and in vitro experiments. Our results highlight the thera-peutic benefits of ICS-II targeting VSMC phenotypic transition and sup-port the potential o...
ORGANISM(S): Rattus Norvegicus 
2022-05-05 | PXD033724 |
ProteomicsProteome of TGF-β1-Induced Human Primary Mesothelial Cells treated with and without BCAT1/2 inhibitor
Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis, primarily driven by TGF-β1-induced mesothelial-to-mesenchymal transition. BCAT1 and BCAT2 are key enzymes in branched-chain amino acid metabolism, yet their specific roles and mechanisms in peritoneal fibrosis remain unc...
ORGANISM(S): Homo Sapiens 
PXD069866 |
ProteomicsR406 binding site on TAK1 identified by MS
We identified of R406 and its pro-drug R788 for the treatment of cancer by inducing necroptosis.
ORGANISM(S): Homo Sapiens 
PXD044897 |
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