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Intestinal polyposis, a precancerous neoplasia, results primarily from an abnormal increase in the number of crypts. Crypts contain intestinal stem cells (ISCs). Thus intestinal polyposis provides an ideal condition for studying stem cell involvement in polyp/tumor formation. Using a conditional kno...
ORGANISM(S): Mus musculus 
identify the potential partners of STC1 at the protein level, we performed mass spectrometry on B16-F10 tumor cells stably expressing FLAG-tagged STC1.
ORGANISM(S): Mus musculus (Mouse) 
2020-12-23 | PXD023251 | Pride
HiSeq poly-A RNAseq of 13 murine bone marrow populations (C57BL/6NJ); 4 HSC, 7 Stromal, Macrophage, Megakaryocyte.
ORGANISM(S): Mus musculus 
N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells
ORGANISM(S): Mus musculus 
Intestinal epithelial stem cells (ISCs) are the focus of recent intense study. Current in vitro models rely on supplementation with the Wnt agonist R-spondin1 to support robust growth, ISC self-renewal, and differentiation. Intestinal subepithelial myofibroblasts (ISEMFs) are important supportive ce...
ORGANISM(S): Mus musculus 
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