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TranscriptomicsTranscription profiling of olfactory epithelium isolated from wild type and SR-A mutant mice at different time points after bilateral olfactory bulbectomy to understand the temporal gene expression patterns.
Sham and bilateral OBX were performed on wild-type and SR-A mutant mice. Tissue collected 2, 8, 16, and 48 hours following OBX. Expression profiles were determined using Affynetrix MG U74Av2 chips. Experiment Overall Design: olfactory epithelium from 3 wild type 6 week old mice and 3 SR-A 6 week old...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-3455 | biostudies-arrayexpress
Transcriptomicsp53 Enables Self Renewal of Nephron Progenitor Cells
p53 limits the self-renewing ability of a variety of stem cells. Here, contrary to its classical role in restraining cell proliferation, we demonstrate a divergent function of p53 in maintenance of self-renewal of the nephron progenitor population in the embryonic mouse kidney. p53-null nephron prog...
ORGANISM(S): Mus musculus 
2015-02-16 | E-GEOD-56253 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of differentiating human erythroblasts
Human erythroblasts purified from cord blood were cultured in vitro and FACS-sorted into five highly purified populations representing distinct differentiation stages:  proerythroblasts, early basophilic erythroblasts, late basophilic erythroblasts, polychromatophilic erythroblasts, and orthochromat...
ORGANISM(S): Homo sapiens 
2013-12-25 | E-GEOD-53635 | biostudies-arrayexpress
ModelsBornheimer2004_GTPaseCycle
This model is according to the paper Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction by Bornheimer et al 2004.The figure 3 is reproduced by Copasi 4.0.19 (development) .It is three-dimensional logarithmic plots sho...
2024-09-02 | BIOMD0000000086 | BioModels
UnknownABCG2-Expressing Clonal Repopulating Endothelial Cells Serve to Form and Maintain Blood Vessels.
Not available
S-EPMC11300167 | biostudies-literature
UnknownBone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking.
Not available
S-EPMC6597218 | biostudies-literature
UnknownThe association between educational attainment and SCA 3 age of onset and disease course.
Not available
S-EPMC10498785 | biostudies-literature
UnknownBone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency.
Not available
S-EPMC7056264 | biostudies-literature
GenomicGENEVA Diabetes Study (NHS/HPFS)

Type 2 diabetes mellitus (T2D) affects approximately 21 million individuals in the U.S., or almost 10% of the U.S. adult population. Because diabetes is determined by both genetic and environmental factors, a better understanding of the etiology of diabetes requires a careful investigation of...

phs000091 | dbGaP
GenomicsEstrogen Receptor Positive Breast Cancer: Aromatase Inhibitor Response Study

Highly variable outcomes are observed in patients with estrogen receptor positive (ER+) breast cancer who undergo preoperative estrogen deprivation therapy with aromatase inhibitors (AI). In this study, 46 tumor and normal genomes and 31 exomes of participants selected from two clinical trials of...

phs000472.v1.p1 | EGA
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