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Protein abundance changes and reversible protein phosphorylation (RPP) play important roles in regulating hypometabolism but have never been documented in overwintering frogs at high altitudes. To test the hypothesis that protein abundance and protein phosphorylation change in response to winter hib...
ORGANISM(S): Nanorana parkeri 
2024-05-22 | PXD042165 | Pride
Different DIPG tumor models have different responses to radiation therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD028285 | Pride
The wild-type p53-induced phosphatase 1 (WIP1) frustrated mice exhibited defects in reproductive organs. This study aimed to understand how Wip1 deficiency affects the spermatogenesis or maturation. We employed the Wip1-/- mouse model and conducted a gel-free iTRAQ LC-MS/MS based quantitative proteo...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-16 | PXD010125 | Pride
The Goto-Kakizak (GK) rat, a nonobese animal model of Type 2 diabetes (T2D), were developed by repeated inbreeding of glucose-intolerent individuals selected from Wistar rats. During their development, GK rats suffer from reduced beta-cell mass and insulin resistance spontaneously (T2D phenotype), w...
ORGANISM(S): Rattus norvegicus 
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