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ProteomicsProteomic Profiling of Mycobacterium tuberculosis in Response to ILE Treatment
This study aims to elucidate the global proteomic changes in Mycobacterium tuberculosis upon treatment with the novel compound ilamycin E(ILE), which targets the Clp protease system. Label-free quantitative proteomics was employed to assess differential protein expression after ILE exposure. The res...
ORGANISM(S): Mycobacterium tuberculosis H37Ra 
2026-02-09 | PXD066355 | Pride
Mycobacterium tuberculosis Tuberculosis Ilamycin e 
ProteomicsProteomic analysis of UCHL1 conditional knockout mice
Proteomic analysis of osteoclast precursor cells of UCHL1 conditional knockout mice and wild-type mice was performed
ORGANISM(S): Mus Musculus 
PXD052578 |
ProteomicsLISS enables immune evasion of colorectal cancers irrespective of MSI status
LISS enables immune evasion of colorectal cancers irrespective of MSI status
ORGANISM(S): Homo Sapiens 
PXD078805 |
ProteomicsIdentification of tumor membrane proteins
Identification of chemotherapy-treated B16-F10 tumor membrane proteins
ORGANISM(S): Mus Musculus 
PXD055424 |
ProteomicsDisruption of STIM1-mediated Ca2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis and lean mass
STIM1 is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in store operated Ca2+ entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STIM1 is indispensable during development, its biological and metabolic functions in mature muscle ...
ORGANISM(S): Mus Musculus (mouse) 
2021-12-30 | PXD030674 | JPOST Repository
ProteomicsDrosophila tracheal cell mass spectrum data
Proteomics of the trachea surface of third instar Drosophila larvae
ORGANISM(S): Drosophila Melanogaster 
2024-02-02 | PXD049142 |
ProteomicsNuclear condensation of CDYL links histone crotonylation and cystogenesis in autosomal dominant polycystic kidney disease
We identify the Kcr sites on histones that are targeted by CDYL in ADPKD cells (WT9-12 cells). We chose to knock out CDYL in WT 9-12 cells (CDYL KO) through CRISPR/Cas9-mediated gene editing to increase the overall levels of histone Kcr. We quantified Kcr modifications on different histone residues ...
ORGANISM(S): Homo Sapiens 
2022-01-17 | PXD031029 |
ProteomicsRIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination
Colorectal cancer (CRC) is a leading cause of cancer death. RIPK2 is identified as a poor prognostic marker, promoting metastasis via bacterial invasion. High RIPK2-expressing tumor cells show enhanced invasiveness. This dataset comprises quantitative proteomic profiles of colorectal cancer (CRC) ce...
ORGANISM(S): Homo Sapiens 
2025-03-03 | PXD061372 |
ProteomicsER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
PXD055020 |
ProteomicsGlobal phosphoproteomic analysis of mouse spermatocytes identified key kinases regulating meiosis
Protein phosphorylation, as one of the most important post-translational modifications, exerts crucial roles in regulating meiosis. However, there is a lack of systemic phosphoproteomic and functional analysis of phosphorylation in the meiosis of spermatocytes. To characterize the phosphorylation ev...
ORGANISM(S): Mus Musculus 
2022-03-07 | PXD032089 |
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