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Systematic investigation into the dynamic alterations in the proteome and phosphoproteome of mycobacteria following overexpression of PknG
ORGANISM(S): Mycolicibacterium Smegmatis Mc2 51 
To explore the role of SCO and its functional mechanism, we measure the SCO-derived peptide in CSF from C57B/6 mice and SCO-ablated mice.
ORGANISM(S): Mus Musculus 
2025-02-04 | PXD040641 |
Triple-negative breast cancer (TNBC) is characterized by its aggressive behavior, with trend to early relapse and metastasis as well as poor survival. Limited therapies and lack of effective therapeutic targets are one of the main challenges in clinical management of TNBC. Histone post-translationa...
ORGANISM(S): Homo Sapiens 
2024-02-01 | PXD049101 |
While linear ubiquitin plays critical roles in multiple cell signaling pathways, few substrates have been identified. Global profiling of linear ubiquitin substrates represents a significant challenge because of the low endogenous level of linear ubiquitination, the none-specific binding of linear p...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031600 |
To understand how Lon protease 1(Lonp1) knockin promotes prostate cancer metastasis in vivo, we performed proteomic analysis on prostates extracted from 40-week-old wild-type (WT), Lonp1KI, Pten-/- and Pten-/-; Lonp1KI mice.
ORGANISM(S): Mus Musculus 
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
Zinc is an essential trace micronutrient and exerts important physiological and biochemical roles. Zinc deficiency is a global public-health problem. Standing untreated zinc deficiency can cause series adverse effects, including growth retardation, poor appetite, delayed sexual development, impaired...
ORGANISM(S): Rattus Norvegicus 
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