For metabolic profiling of human CD4+ T cells，stable isotope labeling (SIL) and metabolomics SIL experiments were performed with in vitro-activated T cells using liquid chromatography (LC) coupled to mass spectrometry (MS).
For metabolic profiling of mouse CD4+ T cells, stable isotope labeling (SIL) experiments were performed with in vitro-activated T cells using gas chromatography (GC) coupled to mass spectrometry (MS).
Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
In this study, we performed the first large-scale nuclear proteome analysis of wheat developing grains under water deficit by label-free based quantitative proteomic approach.
In the current study, we expanded our previous work to identify miRNAs implicated in the myogenesis regulation through the comparison of miRNAs transcriptome in skeletal muscle tissues between broilers and layers. To address that, we firstly performed Solexa deep sequencing to profile miRNAs express...
In the current study, we expanded our previous work to identify miRNAs implicated in the myogenesis regulation through the comparison of miRNAs transcriptome in skeletal muscle tissues between broilers and layers. miRNA expression studies of two different intra-species breeds
In this study, a HFD-induced lipid metabolism disorder model was established in C57BL/6 mice in vivo, and a palmitic acid (PA)-induced hepatocyte lipid accumulation model was constructed in HepG2 cells in vitro. Using component identification, network pharmacology, transcriptome sequencing, molecula...
