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MetabolomicsMirabegron displays anticancer effects by globally browning adipose tissues

Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development by targeting adipose metabolism remain larg...

2023-11-08 | MTBLS8682 | MetaboLights
ProteomicsMass spectrometry (MS) datasets of PURPL RNA pulldown samples in A375 cells
We performed PURPL RNA pulldown followed by MS analysis to identify purpl-interacting proteins in A375 cells.With high performance liquid chromatography-mass spectrometry (HPLC-MS), the binding protein of PURPL from RNA pull down was detected by removing non-specific protein which were binding with ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028863 | Pride
Human a375 cells lc-ms 
MetabolomicsBrown-fat-mediated tumour suppression by cold-altered global metabolism

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering thermogenesis of adipose tissues. Most cancers use glycolysis to harness energy for their infinite growth, invasion and metastasis. Activation of thermogenic metabolism in brown adipose tissue (BAT) by cold an...

2022-08-12 | MTBLS4856 | MetaboLights
ProteomicsHuman Plasma Gel Filtration Fractions MS Data
Mapping Atheroprotective Functions and Related Proteins/Lipoproteins in Size Fractionated Human Plasma
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081547 | MassIVE
ProteomicsColistin resistance in Acinetobacter baumannii MDR-ZJ06 revealed by a multiomics approach
To explore how multiple drug-resistant A. baumannii response to colistin resistance, we compared the genomic, transcriptional and proteomic profile of A. baumannii MDR-ZJ06 to that of induced colistin resistant strain ZJ06-200P5-1.
ORGANISM(S): Acinetobacter baumannii 
2017-03-15 | PXD005265 | Pride
Colistin  acinetobacter baumannii 
TranscriptomicsRNA-seq data in cardiac tissues from cardiomyocyte-specific Acsl4 knockout mice after transverse aortic constriction
In order to investigate the differentially expressed genes in Acsl4 knockout after TAC (Transverse aortic constriction) or sham surgery. The experiment was divided to four groups including sham-operated Acsl4 flox/flox mice (FS), sham-operated Acsl4 knockout mice (KS), TAC-operated Acsl4 flox/flox m...
ORGANISM(S): Mus musculus 
2024-08-26 | E-MTAB-14383 | biostudies-arrayexpress
ProteomicsProteome of extracellular vesicles derived from breast cancer cells
MDA-MB-231 cells were irradiated with 10 Gy X-rays and the medium was harvest for extracellular vesicles isolation 24 hours post-irradiation. Proteins carrying by EVs of irradiated and control cells were then analysed by LC-MS.
ORGANISM(S): Homo Sapiens 
2024-04-22 | PXD051650 |
ProteomicsAffinity purification of TRMT6/61A protein complexes
In order to identify the molecular mechanism leading to the increase of TRMT6/61A complex in aged HSCs, we purified proteins interacting with TRMT6 and TRMT61A via affinity purification. HEK293T cells stably expressing SFB-tagged TRMT6 or SFB-TRMT61A were lysed in NETN buffer (20 mM Tris-HCl [pH 8.0...
ORGANISM(S): Homo Sapiens 
2023-11-30 | PXD047430 |
UnknownThe psychological status of 8817 hospital workers during COVID-19 Epidemic: A cross-sectional study in Chongqing.
Not available
S-EPMC7369013 | biostudies-literature
ProteomicsCo-IP and LC-MS/MS analysis for probing the binding partners of ITGBL1 in fibroblasts
Co-IP, LC-MS/MS and cluster analysis of the binding proteins for targeted ITGBL1 protein using the ITGBL1 antibody or control IgG in ITGBL1-overexpressing WI-38 cells.
ORGANISM(S): Homo Sapiens 
2020-01-19 | PXD017182 |
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