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ProteomicsMice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria
Replication of mammalian mitochondrial DNA (mtDNA) is an essential process that requires high fidelity and control at multiple levels to ensure proper mitochondrial function. Mutations in the mitochondrial genome maintenance exonuclease 1 (MGME1) gene were recently reported in mitochondrial disease ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD009138 | Pride
Mtdna deletions Mgme1 knock out Progeria 
ProteomicsMitochondria enriched proteome from heart of heart Sod2 knockout mice LC MS/MS
Superoxide dismutases (SOD) convert superoxide to hydrogen peroxide and therefore provide an important ROS defence mechanism. SOD2 is the sole superoxide dismutase in mitochondrial matrix and thus SOD2 knockout mice can be utilized to analyse what effects increased oxidative stress has on mitochondr...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-06 | PXD008998 | Pride
C57bl/6n Heart Sod2 Superoxide dismutase 2 Mitochondria Mouse Mnsod2 
UnknownThe genetic and clinical characteristics of WFS1 related diabetes in Chinese early onset type 2 diabetes.
Not available
S-EPMC10241780 | biostudies-literature
UnknownSex- and body mass index-specific reference intervals for serum leptin: a population based study in China.
Not available
S-EPMC9358897 | biostudies-literature
UnknownSurvival of Chinese people with type 2 diabetes and diabetic kidney disease: a cohort of 12 -year follow-up.
Not available
S-EPMC6842464 | biostudies-literature
ProteomicsProteomic Antibacterial Characterization of Flavonoid Xanthohumol and probiotic Clostridium butyricum on Pathogenic Clostridioides difficile
In this study, we evaluated the antimicrobial properties of XN and C. butyricum culture supernatant (CBs) against C. difficile, focusing on their ability to reduce C. difficile adhesion, inhibit growth, and restrict toxin production. Using a dextran sulfate sodium (DSS)-induced Caco-2 intestinal epi...
ORGANISM(S): Clostridioides Difficile 70-100-2010 Clostridioides Difficile Atcc 9689 = Dsm 1296 
PXD069714 |
ProteomicsImmune Responses to multi-frequency of 1.5GHz and 4.3GHz microwave exposure in rats
In this study, we exposed the rats to 1.5 GHz (L10), 4.3 GHz (C10) or multi-frequency (LC10) microwave at an av-erage power density of 10 mW/cm2. Both single and multi-frequency microwave induced slight pathological changes in thymus and spleen. And, the white blood cells (WBCs) and lymphocytes in p...
ORGANISM(S): Rattus Norvegicus 
PXD034706 |
ProteomicsChanges of exosomes expression after long term exposure to 2.856 and 9.375 GHz microwaves
Changes of exosomes expression after long term exposure to 2.856 and 9.375 GHz microwaves.
ORGANISM(S): Rattus Rattus 
2022-09-01 | PXD036462 |
ProteomicsChanges of protein expression after long term exposure to 2.856 GHz and 9.375 GHz microwaves
Changes of protein expression in hippocampus after long term exposure to 2.856 GHz and 9.375 GHz microwaves
ORGANISM(S): Rattus Norvegicus 
2022-08-19 | PXD036155 |
ProteomicsProteomic analysis for In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
Proteomic analysis for In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
ORGANISM(S): Mus Musculus 
PXD035315 |
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