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ProteomicsIntegrative proteomic and phosphoproteomic profiling of testis from Wip1-knockout mice: insights into mechanisms of reduced fertility
Spermatogenesis plays an important role in the mammalian testis, involving in the complex processes of mitosis, meiosis, and spermiogenesis. Spermatogenesis may also be disrupted in the absence of the immunological and ‘fence’ functions of the BTB, resulting in male subfertility or infertility. Mice...
ORGANISM(S): Mus musculus (Mouse) 
2018-11-02 | PXD009220 | Pride
Fertility Proteomic Phosphoproteomic Knockout mice Testis Wip1 
ProteomicsLC-MS/MS proteomic analysis of candidate BATF2-binding proteins
Label-free Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) proteomic analysis of candidate BATF2-binding proteins
ORGANISM(S): Homo Sapiens 
2022-10-27 | PXD037788 |
TranscriptomicsTelomerase subunit TERT regulates MYC stability independent of its role on telomeres (array)
Constitutively active MYC and reactivated telomerase often co-exist in cancers. While the reactivation of telomerase is thought to be essential for replicative immortality, MYC, in conjunction with co-factors, confers several growth advantages to cancer cells. However, it is unclear which co-factors...
ORGANISM(S): Homo sapiens 
2015-04-23 | E-GEOD-60175 | biostudies-arrayexpress
GenomicsTelomerase subunit TERT regulates MYC stability independent of its role on telomeres (ChIP-Seq)
Constitutively active MYC and reactivated telomerase often co-exist in cancers. While the reactivation of telomerase is thought to be essential for replicative immortality, MYC, in conjunction with co-factors, confers several growth advantages to cancer cells. However, it is unclear which co-factors...
ORGANISM(S): Mus musculus 
2015-04-23 | E-GEOD-60223 | biostudies-arrayexpress
ProteomicsStudy on the spatial effect of peripheral ApoE3 on regulating cadmium binding proteome and mechanism of cognitive impairment in the elderly
The experiment utilized a total of 54 five-week-old Sprague-Dawley rats, each weighing approximately 100 grams. These rats were randomly divided into 9 groups, consisting of 27 female and 27 male rats. Based on the intervention dose of cadmium (Cd), the rats were further randomly assigned into 3 mai...
ORGANISM(S): Rattus Rattus 
2025-04-16 | PXD063013 |
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