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ProteomicsEffect of spaceflight on the phenotype and proteome of Escherichia coli
BACKGROUND: Microbial safety has become a research hotspot with the development of manned space technology. Escherichia coli is a conditional pathogen that can cause infectious diseases. Therefore, it is necessary to study the influence of space environment on Escherichia coli. METHODS: Phenotypic e...
ORGANISM(S): Escherichia Coli 
2020-12-16 | PXD023158 |
ProteomicsIntegrated proteomic and Metabolomic analysis to study the effects of spaceflight on Candida albicans
Background: Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study,we aim to explore the phenotypic changes and possible mechanisms of Candida albicans after exposure to spac...
ORGANISM(S): Candida Albicans 
2020-08-27 | PXD016983 |
ProteomicsUBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice
For proteomics analysis, testes of Ube2j2-/- and WT mice were collected on ice, washed once with pre-cooled PBS, dried with absorbent paper, and immediately placed in liquid nitrogen, dry ice, or at -80 ℃. Samples were packed in dry ice and transported to Hangzhou Jingjie Biotechnology Company (PTM ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-05 | PXD063637 | Pride
Meiosis arrest Synaptonemal complex disassembly. Ube2j2 Homologous recombination 
ProteomicsProteomics of intestine in simulated microgravity rats
After 14 days simulated microgravity，rats jejunal mucosa was taken for proteomic study. A total of 1826 proteins were detected, and 335 differentially expressed proteins were detected, of which 190 were up-regulated and 145 were down-regulated.
ORGANISM(S): Rattus Norvegicus 
2020-09-17 | PXD021522 |
ProteomicsGenetic origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Lamprigera Yunnana 
2019-08-30 | PXD015226 |
ProteomicsThe origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Luciola Terminalis 
2019-08-30 | PXD015227 |
ProteomicsMulti-Omics of Spinal Ependymal Tumor
We conducted a multi-omics analysis of 25 patients, comprising 8 with ependymoma, 10 with myxopapillary ependymoma, and 7 with subependymoma, to identify both shared and distinct genomic, transcriptional, and proteomic features among these subtypes.
ORGANISM(S): Homo Sapiens 
2024-09-20 | PXD056112 |
ProteomicsLysine methylation promotes NFAT5 activation upon EGFR activation and predicts response to temozolomide
Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of...
ORGANISM(S): Homo Sapiens 
2022-11-01 | PXD037869 |
ProteomicsIntegrated multi-omics analysis of zinc deficiency
Zinc is an essential trace micronutrient and exerts important physiological and biochemical roles. Zinc deficiency is a global public-health problem. Standing untreated zinc deficiency can cause series adverse effects, including growth retardation, poor appetite, delayed sexual development, impaired...
ORGANISM(S): Rattus Norvegicus 
2019-06-05 | PXD014079 |
ProteomicsHippocampal proteomics analysis of marginal zinc deficiency
Zinc is an essential trace element that is closely related to learning and memory ability. The hippocampus plays an important role in learning and memory and has the highest zinc concentration in the brain. Severe zinc deficiency (zinc-deprived diet) significantly alter hippocampal protein expressio...
ORGANISM(S): Rattus Norvegicus 
2021-10-04 | PXD028998 |
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