Sort   by:  
 Page size 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsNS7a of SADS-CoV promotes viral infection via inducing apoptosis to suppress Type III interferon production
SADS-CoV is a newly discovered swine coronavirus with potential cross-species transmission risk. Although SADS-CoV-induced host cell apoptosis and attenuated innate immunity has been established, the relation between apoptosis and innate immunity remain obscure. Here, we demonstrate that infection o...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-06 | PXD047032 | Pride
Viral replication Swine acute diarrhea syndrome virus (sads-cov) Ns7a Apoptosis Apoptosis inducing factor mitochondria associated 1 (aifm1) Ifn-λ 
ProteomicsRepurposing Lusutrombopag: Unveiling Anti-Staphylococcus aureus Activity in a Novel Oral Thrombopoietin Receptor Agonist
Here are the findings from the DARTs (Drug Affinity Responsive Target Stability) and proteomics studies for Lusutrombopag
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-17 | PXD072172 |
ProteomicsMass Spectrometry Proteomics Reveals Cell Density Affects Drug Treatment Efficacy
using proteomic data to explain the difference induced by cultured cell confluence
ORGANISM(S): Homo Sapiens 
2022-08-18 | PXD036142 |
ProteomicsYAS202410100081-1 Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences_Yongdalsuo Bacterium_Biomass_Standard PRMplus
The experiment used Skyline software to analyze 150 target peptides from 83 target proteins. Detailed quantitative information of the target peptides in the samples is provided in Supplementary Tables 1 and 2. Quantitative information was normalized and corrected using isotopically labeled peptides,...
ORGANISM(S): Clostridium Ljungdahlii Dsm 13528 
2025-12-30 | PXD072554 |
ProteomicsComparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose
The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.
ORGANISM(S): Klebsiella Pneumoniae 1191100241 
2024-11-04 | PXD057506 |
ProteomicsMLS0315771 S. aureus YUSA145 proteomics
Quantitative label-free proteomic analysis investigated the global proteomic response of S. aureus YUSA145 treated with 1/2 × MIC MLS0315771 during the exponential growth phase. The results were obtained after performing principal component analysis (PCA) on the raw data and excluding two replicates...
ORGANISM(S): Staphylococcus Aureus 
2026-01-24 | PXD073535 |
ProteomicsMulti-omics study for drug resistance investigation
Palbociclib is a specific CDK4/6 inhibitor that has been widely applied in multiple tumor types. Different from cytotoxic drugs, the anticancer mechanism of palbociclib mainly depends on cell cycle inhibition. Therefore, the resistance mechanism is different. For clinical cancer patients, drug resis...
ORGANISM(S): Homo Sapiens 
2022-11-30 | PXD038509 |
ProteomicsHSP60-mediated UPRmt overactivation drives triptolide-induced Hepatocellular lipoapoptosis
This study aims to investigate the role of excessive activation of the mitochondrial unfolded protein response (UPRmt) in TP-induced liver injury and to elucidate the mechanism by which HSP60 mediates this process in regulating lipid metabolism disorders.
ORGANISM(S): Mus Musculus 
2026-01-08 | PXD072797 |
ProteomicsMolecular Landscape of Atherosclerotic Plaque Progression: Insights from Proteomics
This dataset comprises proteomic profiles of 87 human carotid atherosclerotic plaques from patients undergoing carotid endarterectomy (CEA). The study employed an integrated approach using Data Independent Acquisition (DIA) proteomics. A total of 87 human carotid plaques were analyzed to identify an...
ORGANISM(S): Homo Sapiens 
2025-03-26 | PXD062283 |
Sort   by:  
 Page size