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ProteomicsRBPs proteome in HEK293 cells, mESCs and mouse organs
Identification of RBPs proteome in HEK293 cells, mouse embryonic stem cells (mESCs) and adult mouse primary organs (brain, heart, lung, kidney, liver)
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-08-26 | PXD037105 | Pride
Rna-binding proteins 
ProteomicsHARD-AP-drived RBPome in HEK293 cells, mouse brain and kidney without UV-crosslinking
Identification of RBPs proteome in HEK293 cells and adult mouse brain and kidney which were not treated with UV light before isolation with HARD beads.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-08-26 | PXD053382 | Pride
Rbpome Hard-ap 
UnknownEvolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis.
Not available
S-EPMC3396513 | biostudies-literature
ProteomicsArabidopsis thaliana seedling lectin enriched LC-MS
this study discovered unique glycoprotein resources responsible for plant salt stress tolerance and suggested crucial roles of Nthis study discovered unique glycoprotein resources responsible for plant salt stress tolerance and suggested crucial roles of N-glycans in regulating salt responsive prote...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-06-29 | PXD006893 | Pride
Glycoproteins Arabidopsis Lc-ms Salt stress 
ProteomicsIdentification of the Key Protein Associated with Different Hair Types in Sheep and Goat
Animal-derived fiber has the characteristics of being light, soft, strong, elastic and a good thermal insulator and it is widely used in many industries and traditional products, so it plays an important role in the economy of some countries. Variations among phenotypes of wool fibers, among species...
ORGANISM(S): Ovis Aries Capra Hircus 
PXD036685 |
TranscriptomicsThe Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
Pre-mRNA splicing is regulated by developmental and environmental cues, but little is known about how specific signals are transduced in mammalian cells to regulate this critical gene expression step. Here, we report massive reprogramming of alternative splicing in response to EGF signaling. By blo...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-GEOD-37731 | biostudies-arrayexpress
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
ProteomicsProteomics of cardiac tissue of mice after sepsis model
Dysregulated cardiac function after sepsis is common in intensive care unit (ICU) and known to predict poor long-term outcome and increase mortality. Effective therapeutic strategies are largely lacking. Moreover, the pathological feature and the molecular mechanism underlying cardiac dysfunction in...
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041530 |
ProteomicsQuantitative proteomics combine with affinity MS revealed the molecular mechanism of ginsenoside anti-tumor effects
The Tandem Mass Tag (TMT) labeling quantitative proteomics technique acquired 55620 MS/MS spectra that identified 5499 proteins and 3045 modified proteins. Of these identified proteins, 224 differentially expressed proteins and modified proteins were significantly altered in non-small cell lung canc...
ORGANISM(S): Homo Sapiens 
2019-02-17 | PXD020149 |
ProteomicsO-GlcNAcylation Promotes Cerebellum Development and Medulloblastoma Oncogenesis via SHH Signaling
Sonic hedgehog (Shh) signaling plays a critical role in regulating cerebellum development by maintaining the physiological proliferation of granule neuron precursors (GNPs), and its dysregulation leads to the oncogenesis of medulloblastoma. O-GlcNAcylation (O-GlcNAc) of proteins is an emerging regul...
ORGANISM(S): Homo Sapiens 
PXD034270 |
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