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TranscriptomicsGenome-wide Identification of Polycomb Target Genes Reveals a Functional Association of Pho with Scm in Bombyx mori
Polycomb group (PcG) proteins are involved in chromatin modifications for maintaining gene repression that play important roles in the regulation of gene expression, tumorigenesis, chromosome X-inactivation, and genomic imprinting in Drosophila melanogaster, mammals, and even plants. PcG proteins ac...
ORGANISM(S): Bombyx mori 
2012-04-17 | E-GEOD-34246 | biostudies-arrayexpress
MetabolomicsMicroplastics Induce Damage to Cattle and Potential Health Risks Through Microbial Mediation: A Rumen Microbiota-Gut-Liver Axis Perspective_blood

Microplastics pollution is prevalent in livestock environments, especially in ruminant feed. Exposure to microplastics can damage the gastrointestinal barrier, alter microbiota, and lead to organ damage. Despite its impact on cattle farming and potential human health risks, the effects of microp...

2025-09-08 | MTBLS12958 | MetaboLights
MetabolomicsMicroplastics Induce Damage to Cattle and Potential Health Risks Through Microbial Mediation: A Rumen Microbiota-Gut-Liver Axis Perspective_Rumen Fluid

Microplastics pollution is prevalent in livestock environments, especially in ruminant feed. Exposure to microplastics can damage the gastrointestinal barrier, alter microbiota, and lead to organ damage. Despite its impact on cattle farming and potential human health risks, the effects of micropl...

2025-09-08 | MTBLS12959 | MetaboLights
UnknownOptimization of an Efficient Protoplast Transformation System for Transient Expression Analysis Using Leaves of Torenia fournieri.
Not available
S-EPMC9412307 | biostudies-literature
ProteomicsCocoon LC-MS/MS-Silkworm cultivation predating the Silk Road in southern Central Asia (2000 BCE)
We conducted proteomics analyses on three cocoons recovered from the Sapalli Tepe (approximately 2000 to 1500 BCE) site in Uzbekistan. This dataset contains LC-MS/MS data associated with the analysis of cocoons including Sapalli-C-1 (S1), Sapalli-C-2 (S2), Sapalli-C-3 (S3), Bombyx mori (S4), and Bom...
ORGANISM(S): Bombyx mori (Silk moth) 
2026-09-11 | PXD084037 | Pride
Cocoon Lc-ms/ms 
ProteomicsPyroptosis therapy targeting TNBC
Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD053939 | Pride
Mice，4t1 cells，lc-ms/ms 
ProteomicsThe molecular mechanisms of imatinb treatment on acute lung injury in septic mice through proteomic technology
A septicemia model was established by intraperitoneal injection of lipopolysaccharide (LPS), followed by tail vein injection of imatinib in the treatment group and normal saline injection in the control group. Flow cytometry was used to detect inflammatory factors, and hematoxylin staining was used ...
ORGANISM(S): Mus Musculus 
2024-02-27 | PXD050204 |
ProteomicsDIA-Brain-aged- target gene knockout mice
The differences between wild-type mice and target gene knockout mice were analyzed by proteomic tests.
ORGANISM(S): Mus Musculus 
2025-01-13 | PXD059745 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
ProteomicsGuinea pig myopia model ocular posterior pole
Proteomic analyses of the ocular posterior pole tissues at 6 weeks after induction of form-deprived myopia and lens-induced myopia models in guinea pigs.
ORGANISM(S): Cavia Porcellus 
2022-11-01 | PXD037872 |
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