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TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
UnknownCharacterization of acupuncture on central amino acid metabolism based on targeted neurotransmitter analysis in mice with inflammatory pain.
Not available
S-EPMC12453991 | biostudies-literature
GenomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - Bisulfite-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34657 | biostudies-arrayexpress
ProteomicshiPSC-derived Mesendoderm cells LC-MSMS
NONO deficiency in hiPSCs results in a distinct defect in early cardiomyocyte differentiation. Mechanistically, NONO interacts with HOXA1 and regulates the dynamic expression of key genes during early cardiomyocyte differentiation. ChIP-seq analysis reveals that NONO loss reduces HOXA1 occupancy at ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-28 | PXD072401 | Pride
Lc-msms Mesendoderm Hipsc 
TranscriptomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - small RNA-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34656 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - mRNA-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34655 | biostudies-arrayexpress
ProteomicsPMs-Ti4+-based plasma extracellular vesicles glycoproteomics and its application in lung cancer
PMs-Ti⁴⁺ enables glycoproteomic analysis that integrates EVs capture and in-situ enzymatic digestion. It can directly identify intact N-glycopeptides in plasma EVs. This study reveals protein expression and glycosylation remodeling in plasma EVs from lung cancer
ORGANISM(S): Homo Sapiens 
PXD076361 |
TranscriptomicsCaste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior
Eusocial insects have evolved the capacity to generate adults with distinct morphological, reproductive and behavioural phenotypes from the same genome. Recent studies suggest that RNA editing might enhance the diversity of gene products at the post-transcriptional level, particularly to induce func...
ORGANISM(S): Acromyrmex echinatior 
2014-10-02 | E-GEOD-51576 | biostudies-arrayexpress
TranscriptomicsRegulation of microRNA Expression and Abundance during Lymphopoiesis
Although the cellular concentration of miRNAs is critical to their function, how miRNA expression and abundance are regulated during ontogeny is unclear. We used deep-sequencing to characterize the microRNome from most developing lymphocytes, various hematopoietic cell lineages, and representative m...
ORGANISM(S): Mus musculus 
2010-06-07 | E-GEOD-21630 | biostudies-arrayexpress
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