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ProteomicsIdentification of PAC1 interactome in activated T cells
To examine the molecular mechanisms by which PAC1 suppresses T cell response to antigen, we conducted immunoprecipitation followed by mass spectrometry to characterize PAC1-associated proteins in activated T cells
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD012201 | Pride
Pac1 T cells Interactome 
UnknownEfficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis.
Not available
S-EPMC11608984 | biostudies-literature
ProteomicsSTN1 facilitates metastasis by promoting transcription of EMT-activator ZEB1 in pancreatic cancer
As pancreatic ductal adenocarcinoma (PDAC) poses a formidable clinical challenge, demanding further exploration of its pathogenesis and drugs targeted for metastasis-the main cause of mortality. Here, we identified STN1, a CST complex member crucial for maintaining telomere lengths and genome stabil...
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD062518 | Pride
Pancreatic cancer  stn1  stat3 
ProteomicsIdentification of proteins affected by PTENα under stress conditions by mass spectrometry
Stress granules are known to be related with selective translation. To determine which proteins are regulated by stress granules assembly in Ptenα─/─ MEFs, we performed a mass spectrometry analysis of Ptenα+/+ and Ptenα─/─ MEFs under oxidative stress.
ORGANISM(S): Mus Musculus 
2020-10-03 | PXD021840 |
ProteomicsIdentification of PTENα associated proteins under stress condictions in B16 cells by mass spectrometry
PTENα is the first isoform of tumor suppressor PTEN. To investigate the molecular mechanism by which PTENα modulates cell response to inflammation, we performed pull-down assays with FLAG-tagged proteins coupled with mass spectrometry under condition of H2O2 treatment in B16 cells.
ORGANISM(S): Mus Musculus 
2021-07-13 | PXD040709 |
ProteomicsDeepFLR Facilitates False Localization Rate Control in Phosphoproteomics
Site-specific phosphorylation events affect nearly all the cellular processes and correct phosphosite localization plays an important role in biological or medical health studies. However, direct false localization rate (FLR) control remains challenging in phosphoproteomics. Here, we propose DeepFLR...
ORGANISM(S): Homo Sapiens 
2023-04-04 | PXD037580 |
ProteomicsIn-vivo crosslinking based affinity purification-mass spectrometry for targeting intracellular protein-protein interactions
Comprehensive interactome analysis of targeted proteins is of great significance to understand how pro-teins work together for functional regulation. Until now, affinity purification strategy with mass spec-trometry (AP-MS) has been recognized as the most widely used technique for studying protein-p...
ORGANISM(S): Homo Sapiens 
2022-12-01 | PXD038473 |
ProteomicsPTMC_The proteomic profiles of pyridinium-based strategy for lysine-selective protein modification in live cells
A new bioorthogonal lysine-labeling strategy based on cationic-pyridinium activated ester, which renders the modification of peptides and proteins’ lysine residues with ultrafast kinetics and excellent specificity under aqueous solution, and profiled reactive-lysine proteome in vitro and in live cel...
ORGANISM(S): Homo Sapiens 
2023-10-24 | PXD036388 |
ProteomicsPatient plasma-based immunoproteomics reveals novel Echinococcus granulosus antigens for diagnosis of cystic echinococcosis, LC-MS/MS
Herein, we establish an immuno-proteomics workflow using CE patient tissues and plasma to identify diagnostic Eg antigens. The proteins extracted from the CE surgery tissues were recognized by the patient plasma and identified by mass spectrometry.
ORGANISM(S): Echinococcus Granulosus Granulosus 
2025-11-13 | PXD070671 |
ProteomicsAstrocyte, OPC, OL in rat postnatal development
Proteomic analysis of astrocyte, OPC, OL isolated from postnatal day 5 rat.
ORGANISM(S): Rattus Norvegicus 
2022-05-03 | PXD033729 |
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