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ProteomicsSynaptosome proteome IGF2 enhancer knockout mice
We identified an enhancer element near IGF2 locus that is possibly involved with dopamine function and schizophrenia. A knockout mouse was generated for the enhancer element in the IGF2 locus. We then characterized the striatal synaptosomes ( i.e. biological fraction representing pre- post synaptic ...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-31 | PXD012786 | Pride
Dopamine Schizophrenia Striatum Synaptosome Igf2 
TranscriptomicsMaternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice-the long term restoration
Early-life antibiotic exposure perturbs the intestinal microbiota, alters innate intestinal immunity, and accelerates type 1 diabetes development in the NOD mouse model. Here we found that maternal cecal microbiota transfer (CMT) to NOD mice with early-life antibiotic perturbation partially rescued ...
ORGANISM(S): Mus musculus 
2021-09-02 | E-MTAB-9982 | biostudies-arrayexpress
TranscriptomicsMaternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice-the short term restoration
To more directly understand the mechanisms by which CMT reduced 1PAT-induced T1D development, we examined P23 ileal gene expression profile of Non-obese diabetic mice by RNAseq. There 3 treatments C, 1P and CMT, and each treatment has 4 mice.
ORGANISM(S): Mus musculus 
2021-09-02 | E-MTAB-9981 | biostudies-arrayexpress
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