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MetabolomicsMetabolome of pig endometrium and placenta.

Neonatal mortality is mostly due to a reduced piglet maturity. An essential question for adaptation to extra-uterine environment lies in the optimization of the crosstalk between maternal and fetal genomes for a distribution of resources that allows fetuses to express healthier phenotypes at birt...

2025-06-30 | MTBLS3091 | MetaboLights
MetabolomicsPlasma 1H-NMR metabolic and amino acid profiles of newborn piglets from two lines divergently selected for residual feed intake

Together with environmental factors, physiological maturity at birth is a major determinant for neonatal survival and postnatal development in mammalian species. Maturity at birth is the outcome of complex mechanisms of intra-uterine development and maturation during the end of gestation. In pig ...

2023-02-16 | MTBLS2137 | MetaboLights
MetabolomicsThe maturity in fetal pigs using a multi-fluid metabolomic approach
In mammalian species, the first days after birth are an important period for survival and the rates of mortality before weaning are high. In pigs, the perinatal deaths average 20% of the litter, with important economic and societal consequences. Among the factors influencing piglet survival at birth...
2020-07-07 | MTBLS1541 | MetaboLights
TranscriptomicsMuscle Transcriptomic Investigation of Late Fetal Development Identifies Candidate Genes for Key Roles in Piglet Maturity
To further knowledge of piglet maturity, we have developed a microarray analysis to describe biological processes and to find candidate genes for key roles in piglet maturity. The objective was to identify which genes and biological processes are specifically involved in the difference between two e...
ORGANISM(S): Sus scrofa 
2014-09-19 | E-GEOD-56301 | biostudies-arrayexpress
TranscriptomicsExpression data from chick embryos overexpressing NEUROG2 or NEUROG2AQ in the neural tube
The proneural NEUROG2 is essential for neuronal commitment, cell cycle exit and neuronal differentiation. Characterizing genes networks regulated downstream of NEUROG2 is therefore of prime importance. To identify NEUROG2 early response genes, we combined gain of function in the neural tube with a g...
ORGANISM(S): Gallus gallus 
2012-05-04 | E-GEOD-37782 | biostudies-arrayexpress
TranscriptomicsGenetic variability of transcript abundance in pig peri-mortem skeletal muscle: eQTL localized genes involved in stress response, cell death, muscle disorders and metabolism.
BACKGROUND: The genetics of transcript-level variation is an exciting field that has recently given rise to many studies. Genetical genomics studies have mainly focused on cell lines, blood cells or adipose tissues, from human clinical samples or mice inbred lines. Few eQTL studies have focused on a...
ORGANISM(S): Sus scrofa 
2011-11-10 | E-GEOD-26924 | biostudies-arrayexpress
TranscriptomicsCharacterization of the gene expression profile of porcine iPS-like cells derived by two reprogramming techniques from translocated t(Y;14) fibroblasts
In the present study we compare the effect of integrative and non-integrative strategies on pluripotency during pig somatic cells reprogramming to pluripotency. Microarray analysis was used to compare the gene expression profile of non reprogrammed porcine embryonic fibroblasts (PEF) and of iPS-like...
ORGANISM(S): Sus scrofa 
2016-07-03 | E-GEOD-71792 | biostudies-arrayexpress
TranscriptomicsComparative effect of DON and plant or microbial biotransformation of DON on gene expression of piglets jejunal explants
Deoxynivalenol (DON) is a frequent mycotoxin in grains, produced by Fusarium fungi, which demonstre multiple side effects such as modulation of immune responses, reduced feed intake and weight gain or impairment of the intestinal barrier function. Among animal species, pigs are the best model for hu...
ORGANISM(S): Sus scrofa domesticus 
2016-07-20 | E-GEOD-66918 | biostudies-arrayexpress
TranscriptomicsDevelopment of Laser Capture Microdissection to study the gene expression of the sheep early ovarian folliculogenesis
Background Correct achievement of early ovarian folliculogenesis is a crucial phase for further ovarian function. This process is closely regulated by cell-cell interactions and coordinated expression of genes from oocyte and granulosa cells. But, despite of the large number of studies, little is kn...
ORGANISM(S): Bos taurus 
2011-07-01 | E-GEOD-25652 | biostudies-arrayexpress
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