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ProteomicsProteomic changes linked to the limbic stage of AD
Alzheimer's disease (AD) is a neurodegenerative disorder and the most common cause of dementia worldwide. In AD, neurodegeneration spreads throughout the brain cortex in a gradual and predictable pattern, causing progressive memory decline and cognitive impairment. Here, we conducted proteomic, acet...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD027173 | Pride
Neuroinflammation Proteomics Limbic stage Phosphoproteomics Alzheimer's disease 
GenomicsmRNA signatures of a T-cell driven Limbic Encephalitis mouse model
mRNA signatures of a T-cell driven Limbic Encephalitis mouse model
PRJNA1297598 | ENA
UnknownTopological Dissection of Proteomic Changes Linked to the Limbic Stage of Alzheimer's Disease.
Not available
S-EPMC8546208 | biostudies-literature
TranscriptomicsmRNA signatures of a T-cell driven Limbic Encephalitis mouse model
To determine the key transcription factors and molecular pathways involved in Limbic Encephalitis (LE), we analyzed immune cell-driven transcriptional changes in a newly developed mouse model of CD8+ T cell-mediated LE. This murine model (OVA-CD8+ LE) recapitulates the essential phenotypic features ...
ORGANISM(S): Mus musculus 
2026-07-09 | GSE303749 | GEO
UnknownLimbic system synaptic dysfunctions associated with prion disease onset.
Not available
S-EPMC11662616 | biostudies-literature
UnknownPure argyrophilic grain disease revisited: independent effects on limbic, neocortical, and striato-pallido-nigral degeneration and the development of dementia in a series with a low to moderate Braak stage.
Not available
S-EPMC11290173 | biostudies-literature
UnknownAltered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia.
Not available
S-EPMC9814421 | biostudies-literature
UnknownFunctional dysconnectivity of the limbic loop of frontostriatal circuits in first-episode, treatment-naive schizophrenia.
Not available
S-EPMC6866515 | biostudies-literature
UnknownMorphological changes of the limbic system associated with acute and chronic low-back pain: A UK biobank imaging study.
Not available
S-EPMC10947961 | biostudies-literature
UnknownOld age genetically confirmed frontotemporal lobar degeneration with TDP-43 has limbic predominant TDP-43 deposition.
Not available
S-EPMC8576062 | biostudies-literature
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