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UnknownA wrinkled structure of gold film greatly improves the signaling of electrochemical aptamer-based biosensors.
Not available
S-EPMC8693351 | biostudies-literature
UnknownPaeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p.
Not available
S-EPMC6920373 | biostudies-literature
ProteomicsRecoding multiple rare codons enables the simultaneous incorporation of up to five distinct noncanonical amino acids
Expanding the genetic code has revolutionized our ability to study and manipulate biological systems through site-specific incorporation of noncanonical amino acids (ncAAs). However, current methods are primarily limited to single-type ncAA incorporation in mammalian cells owing to translation ineff...
ORGANISM(S): Homo Sapiens 
2025-11-04 | PXD070277 |
ProteomicsNascent proteome reveals key regulators in the development of alcoholic liver disease
Alcoholic liver disease (ALD) poses a significant global health challenge, and the global proteome will change dynamically and dramatically for the response to alcohol stress. However, due to the lack of method for labeling and identification of tissue-specific nascent proteome in living mouse, the ...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD051725 |
UnknownTherapeutic targeting de novo purine biosynthesis driven by β-catenin-dependent PPAT upregulation in hepatoblastoma.
Not available
S-EPMC11914223 | biostudies-literature
ProteomicsReconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression
We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutan...
ORGANISM(S): Mus Musculus 
2024-11-05 | PXD057516 |
ProteomicsPhosphoproteome and proteome of mouse hepatocyte maturation and human hepatic reprogramming
To identify central protein kinases that potentially promote the maturation, we chemically induced liver progenitor cells (CLiPs) from mouse hepatocytes using a previously established protocol, and profiled the phosphoproteome and proteome of freshly isolated primary mouse hepatocytes (MHs) and ALBU...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD035829 |
ProteomicsCell fate decision by a morphogen-transcription factor-chromatin modifier axis
The IP-MS data includes SALL4 IP-MS data with or without BMP4 treatment at day 3 of JGES reprogramming, each group contain 3 repeats.
ORGANISM(S): Mus Musculus 
PXD051433 |
ProteomicsATAD2 is a Potential Immunotherapy Target for Patients with Small Cell Lung Cancer Harboring HLA-A*0201
To identify the immune peptides in SCLC tumour cells that can be processed and presented by HLA-I, we performed LC–MS/MS analysis on 11 SCLC cell lines, representing the heterogeneity of SCLC subtypes. Ten of the cell lines were confirmed positive for HLA-I, and one was HLA-I-deficient. To analyse c...
ORGANISM(S): Homo Sapiens 
2024-11-26 | PXD058303 |
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
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