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MetabolomicsHomeostasis of the biosynthetic E. coli metabolome
Metabolite concentrations vary across conditions and such metabolome changes are relevant for metabolic and gene regulation. Here, we used LC-MS/MS to explore metabolite concentration changes in Escherichia coli. We measured 101 primary metabolites in 19 experimental conditions that include v...
2022-11-02 | MTBLS4249 | MetaboLights
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
ProteomicsAdipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing
Circulating trimethylamine N-oxide (TMAO) participates in the pathogenesis of cardio-metabolic diseases, with hepatic flavin-containing monooxygenase 3 (FMO3) originally regarded as the primary source of TMAO production. Here, we demonstrate that white adipose tissue (WAT) expressed FMO3 and its der...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-23 | PXD066391 | Pride
Macrophage Mouse Inflammasome Adipocyte Fmo3 Tmao 
UnknownKynurenic acid may underlie sex-specific immune responses to COVID-19.
Not available
S-EPMC8432948 | biostudies-literature
UnknownKynurenic acid underlies sex-specific immune responses to COVID-19.
Not available
S-EPMC7491534 | biostudies-literature
UnknownNCI-sponsored trial for the evaluation of safety and preliminary efficacy of 3'-deoxy-3'-[18F]fluorothymidine (FLT) as a marker of proliferation in patients with recurrent gliomas: preliminary efficacy studies.
Not available
S-EPMC4739628 | biostudies-literature
UnknownOptic neuritis as a link between autoimmunity and dementia risk.
Not available
S-EPMC12328802 | biostudies-literature
UnknownKIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma.
Not available
S-EPMC8464548 | biostudies-literature
UnknownMAGI1 as a link between endothelial activation and ER stress drives atherosclerosis.
Not available
S-EPMC6483653 | biostudies-literature
UnknownDiscovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.
Not available
S-EPMC7025382 | biostudies-literature
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