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TranscriptomicsEffects of Lipocalin 2 (Lcn2), iron, and the bacterial siderophore Enterobactin on A549 respiratory cell gene expression
Iron is essential for many cellular processes and is required by bacteria for replication. To acquire iron from the host, pathogenic Gram-negative bacteria secrete siderophores, including Enterobactin (Ent). However, Ent is bound by the host protein Lipocalin 2 (Lcn2), preventing bacterial reuptake ...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54962 | biostudies-arrayexpress
ProteomicsLipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control
Members of the lipocalin protein family serve as biomarkers for kidney disease and acute phase inflammatory reactions, and are under pre-clinical development for the diagnosis and therapy of allergies. However, none of the lipocalin family members has made the step into clinical development, mostly ...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-02 | PXD022682 | Pride
Lipocalin 13 Metabolic diseases Type 2 diabetes Hepatokine Obesity 
ProteomicsGlareosin: a novel sexually dimorphic urinary lipocalin in the bank vole, Myodes glareolus, C4PR_LIV
The urine of bank voles (Myodes glareolus) contains substantial quantities of a small protein that is expressed at much higher levels in males than females, and at higher levels in males in the breeding season. This protein was purified and completely sequenced at the protein level by mass spectrome...
ORGANISM(S): Myodes glareolus (Bank vole) (Clethrionomys glareolus) 
2017-09-13 | PXD006645 | Pride
Primary sequence Metabolic labelling Obp Mass spectrometry Lipocalin Bank vole Glareosin Myodes glareoulus Odorant binding protein 
GenomicsLipocalin-2 deficiency attenuates acute lung inflammation
Lipocalin-2 deficiency attenuates acute lung inflammation
PRJNA814910 | ENA
TranscriptomicsTranscription profiling of wild type and lipocalin knock-out Arabidopsis plants grown at normal or low temperatures
Effect of lipocalin gene knock-out on gene expression and stress tolerance under normal growth temperature and under low temperature exposure
ORGANISM(S): Arabidopsis thaliana 
2008-03-31 | E-TABM-430 | biostudies-arrayexpress
TranscriptomicsMycobacteria-induced anaemia: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2 but not hepcidin
Anaemia is a frequent complication of chronic infectious diseases but the exact mechanisms by which it develops remain to be clarified. In the present work, we used a mouse model of mycobacterial infection to study molecular alterations of iron metabolism. We show that four weeks after infection wit...
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-20024 | biostudies-arrayexpress
Proteomics• Optimal Functioning of the Lipopolysaccharide Transport Bridge Depends on a Ternary Complex Between the Lipocalin YedD and the LptDE Translocon
The outer membrane is an efficient permeability barrier that protects Gram-negative bacteria against external assaults including many antibiotics. The unique permeability features of the outer membrane are due to the presence of lipopolysaccharide (LPS) molecules in its outer leaflet. LPS localizati...
ORGANISM(S): Escherichia coli 
2025-07-09 | PXD059551 | Pride
Lps Bacteria Lipocalin Outer membrane Translocon 
ProteomicsLipocalin-2+ Mast Cells in Lymph Nodes Promote Tumor Progression via a Mitochondrial-derived Peptide
Mast cells (MCs) play a pivotal role in barrier tissues that connect to the external environment, but their distribution and functions in lymph nodes (LNs) remain largely unclear, especially during the tumor progression. Here, using single-cell RNA sequencing (scRNA-seq), photoconversion tumor cell ...
ORGANISM(S): Mus Musculus 
2024-12-19 | PXD059036 |
TranscriptomicsLipocalin-2 deficiency attenuates acute lung inflammation
Lipocalin-2 promotes acute lung inflammation
ORGANISM(S): Mus musculus 
2023-02-28 | GSE198406 | GEO
UnknownTear Lipocalin and Lipocalin-Interacting Membrane Receptor.
Not available
S-EPMC8417070 | biostudies-literature
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