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TranscriptomicsRNA-seq of mutant Mycobacterium neoaurum producing steroid intermediates compared with wild-type strain
Mycobacterium neoaurum (Mn), an efficient sterol consumer, has been modified to transform sterols to produce valuable steroid intermediates, which can be widely used as precursors in the synthesis of steroid hormones.To deepen our understand of the underlying mechanisms of Mn to the in vitro and in ...
ORGANISM(S): Mycobacterium neoaurum 
2018-05-26 | E-MTAB-6789 | biostudies-arrayexpress
UnknownGut microbial diversity among Yorkshire, Landrace and Duroc boars and its impact on semen quality.
Not available
S-EPMC9789229 | biostudies-literature
UnknownMicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice.
Not available
S-EPMC4580638 | biostudies-literature
ProteomicsQuantitative analysis of the global proteome of heart tissue in septic shock
Nowadays, sepsis and septic shock have become major public health problems, which are the main cause of death among patients admitted to the intensive care units. Notably, myocardial dysfunction during sepsis, usually called sepsis-induced myocardial depression, is common in septic shock patients wh...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-19 | PXD029649 | Pride
Shock Sepsis Proteome Myocardial depression 
UnknownRole of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.
Not available
S-EPMC10726594 | biostudies-literature
ProteomicsCheA pupylation sites identified by SPIDER assay
We used CheAs and biotin-CheZ to validate the efficiency of SPIDER capturing protein-protein interaction. Pupylation sites on WT CheAs after SPIDER assay was identified by LC-MS/MS analysis, by searching for an additional mass of ~243 Da, which represents the three C-terminal residues of Pup, i. e.,...
ORGANISM(S): Escherichia Coli 
2021-06-04 | PXD026509 |
ProteomicsPupylation sites on protein Sox2
As a test for the effectiveness of SPIDER with RNA-protein pairs, We used Sox2 and specific biotin-DNA and biotin-RNA to validate the efficiency of SPIDER capturing protein-nucleic acid interaction. Pupylation sites on Sox2 after SPIDER assay was identified by LC-MS/MS analysis, by searching for an ...
ORGANISM(S): Homo Sapiens 
2021-06-04 | PXD026517 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
2022-10-28 | PXD021583 |
ProteomicsMass spectrometry to exam noval receptors of the The Omicron Variant of SARS-CoV-2 RBD captured by SPIDER
We used SPIDER to examine the cell-surface receptors for specific ligands while these receptors were in their native membranes within intact cells in culture. Here we coupled the SPIDER assay with biotinylated RBD of the Omicron Variant of SARS-CoV-2 and biotinylated RBD of SARS-CoV-2. Then we perfo...
ORGANISM(S): Homo Sapiens Chlorocebus Sabaeus 
2022-01-18 | PXD031035 |
ProteomicsPupylation sites on protein GFP-PupE
Characterization of GFP-Pup after Pupylation assays by mass spectrometry.
ORGANISM(S): Mycobacterium Tuberculosis H37rv_2009 
2021-06-04 | PXD026478 |
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