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ProteomicsIdentification and quantification of KPNA2 phosphorylation and interactome in response to hydrogen peroxide-induced oxidative stress
Karyopherin α 2 (KPNA2, importin α1) is involved in the nuclear import of proteins and participates in cellular processes and accumulates in the nucleus under cellular stresses including hydrogen peroxide-indeced oxidative stress via unknown mechanisms. We performed the immunoprecipitation assay and...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051121 | Pride
Npm1 Hydrogen peroxide Silac Phosphorylation Kpna2 
ProteomicsQuantitative tissue proteomics analysis of primary lung adenocarcinoma
In this study, we generated a quantitative lung tissue proteome dataset from lung adenocarcinoma and adjacent normal lung tissues by using iTRAQ labeling combined with 2D-LC-MS/MS. Based on pathway and network analyses, protein expression profiles released in the public Human Protein Atlas database,...
ORGANISM(S): Homo sapiens (Human) 
2016-05-12 | PXD004077 | Pride
Lung cancer  adenocarcinoma  lymph node metastasis  biomarkers  ero1l  nars  itraq 
ProteomicsIdentification of Golgin Imh1 phosphorylation residues under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031562 | Pride
Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsInvestigating the upstream signaling of Imh1 phosphorylation under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031563 | Pride
Ire1 Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsQuantitative proteomics reveals inflammatory signaling in golgin-97 knockout-mediated breast cancer progression
The Golgi apparatus serves as a central hub for trafficking, regulating the anterograde transport and modification of proteins and lipids, or recycling extracellular proteins via retrograde transport through endosomes. Several Golgi-localized proteins have been reported to be involved in regulating ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD056499 | Pride
Breast cancer Golgin-97 Inflammatory Golgi Metastasis 
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownTen months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort.
Not available
S-EPMC8791638 | biostudies-literature
UnknownImplementation of Recommendations on the Use of Corticosteroids in Severe COVID-19.
Not available
S-EPMC10751594 | biostudies-literature
UnknownThrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry.
Not available
S-EPMC10439444 | biostudies-literature
UnknownAt-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods.
Not available
S-EPMC11252333 | biostudies-literature
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